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Structure of the Flavivirus Genome

  • Chapter
The Togaviridae and Flaviviridae

Part of the book series: The Viruses ((VIRS))

Abstract

The flaviviruses were formerly classified as a genus in the family Togaviridae. They have now been elevated to family status, family Flaviviridae, in part because of differences in replication and assembly (Westaway, 1980) (Chapter 11) and in part because their genome structure is quite different from that of the alphaviruses (Rice et al., 1985) (compare with Chapter 3). With the determination of the complete nucleotide sequence of the yellow fever virus genome and a large portion of the Murray Valley encephalitis virus genome, it has become clear that these viruses represent a distinct group among the plus-stranded RNA viruses. This chapter will focus on the implications of these and other recent sequence data on flavivirus gene expression, replication, and evolution.

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  1. Division of Biology, California Institute of Technology, Pasadena, California, 91125, USA

    Charles M. Rice, Ellen G. Strauss & James H. Strauss

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    Sondra Schlesinger  & Milton J. Schlesinger  & 

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Rice, C.M., Strauss, E.G., Strauss, J.H. (1986). Structure of the Flavivirus Genome. In: Schlesinger, S., Schlesinger, M.J. (eds) The Togaviridae and Flaviviridae. The Viruses. Springer, Boston, MA. https://doi.org/10.1007/978-1-4757-0785-4_10

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  • DOI: https://doi.org/10.1007/978-1-4757-0785-4_10

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4757-0787-8

  • Online ISBN: 978-1-4757-0785-4

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