Regulation of H-2 Class I Gene Expression in Virus Transformed and/or Infected Cells
Our group first documented that viral infections and virus-induced transformations can significantly affect class I gene expression. These virally-induced alterations in H-2 (class I) antigen expression were shown to play a striking role in resistance to neoplasia18. Similar observations which have recently been made by numerous investigators in a variety of other systems 6, 8, 12, 24, 26.
KeywordsAntigen Expression Viral Sequence Histocompatibility Antigen Susceptible Mouse Resistant Mouse
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