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The Importance of Energy Intake for Preventing the Accumulation of Guanidino Compounds in Patients with Chronic Renal Failure

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Guanidines

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Abstract

It is now recognized that methylguanidine (MG) and guanidinosuccinic acid (GSA) are the prototypes of low molecular weight uremic toxins1,2. There remain, however, many problems concerning the origin of these substances. This study is designed to evaluate the effect of dietary energy intake in preventing the accumulation of MG and GSA. We report that in the presence of a high energy intake the serum levels of MG, GSA, and urea nitrogen diminish and the nutritional status improves.

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References

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Author information

Authors and Affiliations

  1. The Second Department of Internal Medicine, The Jikei University School of Medicine, 3-25-8 Nishishibashi, Minato-ku, Tokyo, Japan

    Seiji Fujiwara, Toshiyuki Nakano, Kazuo Isoda & Tadashi Miayahara

Authors
  1. Seiji Fujiwara
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  2. Toshiyuki Nakano
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  3. Kazuo Isoda
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  4. Tadashi Miayahara
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Editor information

Editors and Affiliations

  1. Inst. for Neurobiology, Okayama University Medical School, Okayama 700, Japan

    Akitane Mori

  2. The Bronx Lebanon Hospital Center, Bronx, New York, USA

    B. D. Cohen

  3. Laboratory of Neurochemistry, Born-Bunge Foundation, Universitaire Instelling Antwerpen, 2610, Wilrijk, Belgium

    A. Lowenthal

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© 1985 Springer Science+Business Media New York

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Fujiwara, S., Nakano, T., Isoda, K., Miayahara, T. (1985). The Importance of Energy Intake for Preventing the Accumulation of Guanidino Compounds in Patients with Chronic Renal Failure. In: Mori, A., Cohen, B.D., Lowenthal, A. (eds) Guanidines. Springer, Boston, MA. https://doi.org/10.1007/978-1-4757-0752-6_33

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  • DOI: https://doi.org/10.1007/978-1-4757-0752-6_33

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4757-0754-0

  • Online ISBN: 978-1-4757-0752-6

  • eBook Packages: Springer Book Archive

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