Guanidines pp 295-308 | Cite as

Possibility of a Common Metabolic Pathway for the Production of Methylguanidine and Dimethylamine in Chronic Renal Failure

  • Fumitake Gejyo
  • Sadao Baba
  • Yoko Watanabe
  • Bellamkonda K. Kishore
  • Yasushi Suzuki
  • Masaaki Arakawa


It is well known that various nitrogenous metabolites accumulate in the blood of uremic patients1,2. These substances, which occur in uremic blood in elevated concentrations, are considered to be toxic and to give rise to many uremic symptoms.


Chronic Renal Failure Succinic Acid Choice Reaction Time Uremic Patient Nitrogenous Metabolite 
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Copyright information

© Springer Science+Business Media New York 1985

Authors and Affiliations

  • Fumitake Gejyo
    • 1
  • Sadao Baba
    • 2
  • Yoko Watanabe
    • 2
  • Bellamkonda K. Kishore
    • 1
  • Yasushi Suzuki
    • 1
  • Masaaki Arakawa
    • 1
  1. 1.Department of Medicine (II)Niigata University School of Medicine, College of Biomedical Technology Niigata UniversityNiigata 951Japan
  2. 2.Department of Medical TechnologyCollege of Biomedical Technology Niigata UniversityNiigata 951Japan

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