Guanidines pp 105-112 | Cite as

The Role of the Liver as a Significant Modulator of the Serum Guanidinoacetic Acid Level in Man

  • Hiroaki Muramoto
  • Yohei Tofuku
  • Mitsuhiko Kuroda
  • Ryoyu Takeda


The metabolism of guanidinoacetic acid (GAA) may be affected by the status of both the kidney and the liver, as GAA is synthesized in the kidney and metabolized to creatine in the liver’. Little attention has been focused on GAA metabolism in patients with liver damage, although there have been many studies on GAA metabolism in uremic patients2,34


Liver Cirrhosis Acute Renal Failure Chronic Renal Failure Liver Damage Renal Failure Patient 
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Copyright information

© Springer Science+Business Media New York 1985

Authors and Affiliations

  • Hiroaki Muramoto
    • 1
  • Yohei Tofuku
    • 1
  • Mitsuhiko Kuroda
    • 1
  • Ryoyu Takeda
    • 1
  1. 1.Department of Internal Medicine (II), School of MedicineKanazawa UniversityKanazawa CityJapan

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