Hydrophilic/Hydrophobic Control of Steroid Release from a Cortisol — Polyglutamic Acid Sustained Release System

  • N. Tani
  • M. Van Dress
  • J. M. Anderson


Biodegradable polymer formulations which allow delivery of biologically active agents to a target organ or organism at controlled rates over a prolonged period of time have been developed and studied.1,2 These biodegradable controlled-release systems offer the distinct advantage that no residual polymer remains following release of the drug and degradation of the polymer.


Release Rate Release Behavior Constant Release Buffer Mixture Water Permeation 
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Copyright information

© Springer Science+Business Media New York 1981

Authors and Affiliations

  • N. Tani
    • 1
  • M. Van Dress
    • 1
  • J. M. Anderson
    • 1
  1. 1.Department of Macromolecular ScienceCase Western Reserve UniversityClevelandUSA

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