Abstract
This paper will review some recent developments and trends of thought on the energetics, mechanism, and dynamics of electron transport and oxidative phosphorylation, as well as some aspects of the interplay between the mitochondrial and cytosolic compartments of cells basic to an understanding of metabolic regulation.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Adolfsen, R. and Moudrianakis, E. (1976). Binding of adenine nucleotides to the purified 13S coupling factor of bacterial oxidative phosphorylation. Arch. Biochem. Biophys. 172: 425433.
Boyer, P.D. (1965). Carboxyl activation as a possible common reaction in substrate-level and oxidative phosphorylation and in muscle contraction. In: T.E. King, H.S. Mason, and M. Morrison (Eds.) Oxidases and Related Redox Systems. pp. 994–1008. Wiley, New York.
Boyer, P.D., Smith, D.J., Rosing, J., and Kayalar, C. (1975). Bound nucleotides and conformational changes in oxidative and photophosphorylation. In: E. Quagliariello, S. Papa, F. Palmieri, E.C. Slater, and N. Siliprandi (Eds.) Electron Transfer Chains and Oxidative Phosphorylation. pp. 361–372. North-Holland, Amsterdam.
Brand, M.D. and Lehninger, A.L. (1977). H+/ATP ratio during ATP hydrolysis by mitochondria: Modification of the chemiosmotic theory. Proc. Nat. Acad. Sci. 74: 1955–1959.
Brand, M.D., Chen, C-H, and Lehninger, A.L. (1976). Stoichiometry of H+ ejection during respiration-dependent accumulation of Cat+ by rat liver mitochondria. J. BioZ. Chem. 251: 968–974.
Brand, M.D., Reynafarje, B., and Lehninger, A.L. (1976a). Reevaluation of the H+/site ratio of mitochondrial electron transport with the oxygen pulse technique. J. Biol. Chem. 251: 5670–5679.
Brand, M.D., Reynafarje, B., and Lehninger, A.L. (1976b). Stoichiometric relationship between energy-dependent proton ejection and electron transport in mitochondria. Proc. Nat. Acad. Sci. 73: 437–441.
Chance, B. (1977). Electron transfer: Pathways, mechanisms, and controls. Ann. Rev. Biochem. 46: 967–980.
Chance, B. (1972). The nature of electron transfer and energy coupling reactions. FEBS Lett. 23: 3–20.
Ernster, L., and Lee, C.P. (1964). Biological oxidoreductions Ann. Rev. Biochem. 33: 729–788.
Klingenberg, M. (1972). ATP synthesis and adenine nucleotide transport in mitochondria. In: S.G. Van den Bergh, P. Borst, L.L.M. Van Deenen, J.C. Riemersma, E.C. Slater, and J.M. Tager (Eds.) Mitochondria: Biogenesis and Bioenergetics. Biomembranes: Molecular Arrangements and Transport Mechanisms. pp. 147–162. North-Holland, Amsterdam.
Klingenberg, M. (1970). Metabolite transport in mitochondria: An example for intracellular membrane function. Essays in Biochem. 6: 119–159.
Lehninger, A.L. (1975). Biochemistry. Worth Publishers, Inc., New York.
Lehninger, A.L. (1970). Mitochondria and calcium ion transport. Biochem. J. 119: 129–138.
Mitchell, P. (1968). Chemiosmotic Coupling and Energy Transduction. Glynn Research Ltd., Bodmin, England.
Mitchell, P. (1966). Chemiosmotic coupling in oxidative and photosynthetic phosphorylation. Biol. Rev. 41: 445–502.
Mitchell, P. and Moyle, J. (1968). Proton translocation coupled to ATP hydrolysis in rat liver mitochondria. Eur. J. Biochem. 4: 530–539.
Mitchell, P. and Moyle, J. (1967). Respiration-driven proton dislocation in rat liver mitochondria. Biochem. J. 105: 1147–1162.
Pedersen, P.L. (1975). Mitochondrial adenosine triphosphatase. J. Bioenergetics 6: 243–275.
Reynafarje, B., Brand, M.D., and Lehninger, A.L. (1976). Evaluation of the H+/site ratio of mitochondrial electron trans- port from rate measurements. J. Biol. Chem. 251: 7442–7451.
Rossi, C.S. and Lehninger, A.L. (1964). Stoichiometry of respir- atory stimulation, accumulation of Ca++ and phosphate, and oxidative phosphorylation in rat liver mitochondria. J. BioZ. Chem. 239: 3971–3980.
Rottenberg, H. (1970). ATP synthesis and electrical membrane potential in mitochondria. Sur. J. Biochem. 15: 22–28.
Slater, E.C. (1976). Intra-and extramitochondrial phosphorylation potentials. In: J.M. Tager, H.D. Soling, and J.R. Williamson (Eds.), Use of Isolated Liver Cells and Kidney Tubules in Metabolic Studies. pp. 65–77. North-Holland, Amsterdam.
Slater, E.C. (1975). Components of electron-transfer chains. In: E. Quagliariello et al. (Eds.) Electron Transfer Chains and Oxidative Phosphorylation. pp. 3–14. North-Holland, Amsterdam.
Slater, E.C. (1974). Electron transfer and energy conservation. In: L. Ernster, R.W. Estabrook, and E.C. Slater (Eds.) Dynamics of Energy-Transducing Membranes. pp. 1–20. Elsevier, Amsterdam.
Tager, J.M., Akerboom, T.P.M., Hoek, J.B., Meijer, A.J., Vaartjes, W., Ernster, L., and Williamson, J.R. (1975). Ammonia and energy metabolism in isolated mitochondria and intact liver cells. In: F.A. Hommes and C.J. Van den Berg (Eds.) Development of Energy Metabolism. pp. 63–72. Academic Press, New York.
Wiechmann, A.H.C.H., Beem, E.P., and van Dam, K. (1975). The relationship between H+ translocation and ATP synthesis in mitochondria. In: E. Quagliariello et al. (Eds.) Electron Transfer Chains and Oxidative Phosphorylation. pp. 335–342. North-Holland, Amsterdam.
Williams, R.J.P. (1975). Protein connections between protons, electrons, and ATP. In: E. Quagliariello et al. (Eds.) Electron Transfer Chains and Oxidative Phosphorylation. pp. 417–422. North-Holland, Amsterdam.
Williams, R.J.P. (1970). Electron transfer, conformation changes and energy conservation. In: J.M. Tager, S. Papa, E. Quagliariello, and E.C. Slater (Eds.) Electron Transport and Energy Conservation. pp. 7–23. Adriatica, Bari.
Williams, R.J.P. (1961). Possible functions of chains of catalysts. J. Theor. BioZ. 1: 1–17.
Wilson, D.F., Stubbs, M., Veech, R.L., Erecinska, M., and Krebs, H.A. (1974). Equilibrium relations between the oxidation-reduction reactions and the adenosine triphosphate synthesis in suspensions of isolated liver cells. Biochem. J. 140: 5764.
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1979 Springer Science+Business Media New York
About this chapter
Cite this chapter
Lehninger, A.L. (1979). Some Aspects of Energy Coupling by Mitochondria. In: Klachko, D.M., Anderson, R.R., Heimberg, M. (eds) Hormones and Energy Metabolism. Advances in Experimental Medicine and Biology, vol 111. Springer, Boston, MA. https://doi.org/10.1007/978-1-4757-0734-2_1
Download citation
DOI: https://doi.org/10.1007/978-1-4757-0734-2_1
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4757-0736-6
Online ISBN: 978-1-4757-0734-2
eBook Packages: Springer Book Archive