Heritable Cell Cycle Disturbances and Late Recovery in X-Irradiated Murine Lymphoma L5178Y-S Cell Populations in Vitro

  • Janusz Z. Beer
  • Irena Szumiel
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 53)


In the last decade the view has been expressed by several authors (1–4) that ageing of the normal mammalian cells is connected with the prolongation of the mitotic cycle. At the same time it has been shown that ionizing radiation can in vitro (5–10) and in vivo (11,12) induce in mammalian cells, besides the lethal effects, also some heritable damages which retard the cell cycle traverse for considerable number of cell generations.


Cell Generation Late Recovery Murine Lymphoma Inosinic Acid Cell Cycle Traverse 
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Copyright information

© Springer Science+Business Media New York 1975

Authors and Affiliations

  • Janusz Z. Beer
    • 1
  • Irena Szumiel
    • 1
  1. 1.Department of Radiobiology and Health ProtectionInstitute of Nuclear ResearchWarszawa-ZeranPoland

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