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The Use of Arrested Populations of Human Diploid Fibroblasts for the Study of Senescence in Vitro

  • Robert T. Dell’Orco
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 53)

Abstract

In recent years attempts have been made to equate in vivo senescence with the finite lifespan demonstrated by human diploid cells. in vitro (1). While preliminary evidence indicates that it may be possible to use cultured cells as an in vitro model system for cellular aging, several critical questions need to be resolved before any true parallel can be drawn between the in vitro phenomenon and the in vivo process.

Keywords

Cell Strain Population Doubling Calendar Time Human Diploid Fibroblast Young Donor 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media New York 1975

Authors and Affiliations

  • Robert T. Dell’Orco
    • 1
  1. 1.Biomedical DivisionThe Samuel Roberts Nobel Foundation, Inc.ArdmoreUSA

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