Ultrastructural Changes in Senile Muscle

  • V. Hanzlíková
  • E. Gutmann
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 53)


Weight loss and related atrophy is characteristic for all senile tissues. The senile muscle change shows, however, two specific features: (a) it is more marked than that of body weight, (b) it is different in different types of muscles or muscle fibers. The reduction of muscle weight varies in different muscles, some of them being affected relatively very late (for example the deep back muscles). The decrease of muscle weight is due to decrease both in number (1) and diameter (2,3,4) of muscle fibers. On the other hand an increase of incidence of largest fibers diameter was described in the eye muscles and explained as a result of compensatory hypertrophy of myocardium after focal degeneration in some muscle fibers (6).


Extensor Digitorum Longus Muscle Muscle Weight Residual Body Mammalian Skeletal Muscle Lipofuscin Granule 
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Copyright information

© Springer Science+Business Media New York 1975

Authors and Affiliations

  • V. Hanzlíková
    • 1
  • E. Gutmann
    • 1
  1. 1.Institute of PhysiologyCzechoslovak Academy of SciencesPragueCzechoslovakia

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