Abstract
The creatinephosphokinase (CPK) has been intensively studied in human serum of normal individuals and in different pathological conditions, especially in various neuromuscular diseases. In some of them, as in Duchenne myopathy, its activity is significantly increased (1). In human tissues, the highest activity was found in muscle, heart and brain. Very low activity was detected in uterus, gall bladder, pylorus, adrenal and thyroid glands (2) and lung.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Pearce, J. M.S., Pennington, R.J. and Walton, J.N. 1964. Serum enzyme studies in muscle disease. II. Serum kinase activity in normal individuals. J. Neurol. Neurosurg. Psychiat. 27: 961.
Hess, J.W., MacDonald, R.P., Frederick, R.J., Jones, R.N. and Nelly, J. 1964. Serum creatine phosphokinase (CPK) activity in disorders of heart and skeletal muscle. Ann. Int. Med. 61; 1015.
Reporter, M.C., Konigsberg, I.R. and Strehler, B.L. 1963. Kinetics of accumulation of creatine phosphokinase activity in developing embryonic skeletal muscle in vivo and in monolayer culture. Exp. Cell Res. 30: 410.
Coleman, G.R. and Coleman, A.W. 1968. Muscle differentiation and macromolecular synthesis. J. Cell Physiol. 72: 19.
Shainberg, A., Jagil, G. and Jaffe, D. 1971. Alteration of enzymatic activities during muscle differentiation in vitro. Develop. Biol. 25: 1.
Morris, G.E., Cooke, A. and Cole, R.J. 1972. Isoenzymes of creatinephosphokinase during myogenesis in vitro. Exp. Cell Res. 74: 582.
Zalin, R. 1972. Creatine kinase activity in cultures of dif ferentiating myoblasts. Biochem. J. 130: 79.
Macek, M. and Michl, J. 1964. Contribution to the cultivation of human diploid cells. Acta Univ. Car. Med. (Prague) 10: 518.
Macek, M., Rezacova, D. and Kotasek, A. 1972. Simple smear method for the sampling and culturing of embryonal and fetal tissues. Humangenetik 16: 245.
Michl, J. 1961. Metabolism of cells in tissue cultures in vitro. Exp. Cell Res. 23: 324.
Macek, M., Hurych, J. and Chvapil, M. 1967. Total hydroxypro-line in post-mortem tissue cultures. Cytologia 32: 308.
Macek, M., Hurych, J. and Chvapil, M. 1967. The collagen protein formation in tissue cultures of human diploid strains. Cytologia 32,: 426.
Macek, M., Hurych, J. and Řezačová, D 1973. Collagen synthe sis in long term amniotic fluid cell cultures. Nature 243: 289.
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1975 Springer Science+Business Media New York
About this chapter
Cite this chapter
Macek, M., Tomášová, H., Hurych, J., Řezáčová, D. (1975). Creatinephosphokinase in Human Diploid Cell Lines. In: Cristofalo, V.J., Holečková, E. (eds) Cell Impairment in Aging and Development. Advances in Experimental Medicine and Biology, vol 53. Springer, Boston, MA. https://doi.org/10.1007/978-1-4757-0731-1_14
Download citation
DOI: https://doi.org/10.1007/978-1-4757-0731-1_14
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4757-0733-5
Online ISBN: 978-1-4757-0731-1
eBook Packages: Springer Book Archive