Kindling and Memory: The Adrenal System and the Bisected Brain
The formation of memory has been studied in a variety of ways, ranging from permanent brain damage and concomitant memory loss or learning disability, to temporary or reversible interference with memory processes, to treatments resulting in the facilitation of engram formation. All of these approaches have contributed some understanding to the assessment of memory formation. The investigative approach which has been used most extensively has been that of retrograde interference with memory fixation, generally achieved through the vehicle of electroconvulsive shock (ECS). It has been shown that ECS produces a graded disruption in the expression of memory, contingent on how closely in time the ECS treatment follows the learning experience; the closer in time, the greater the memory abolition (e.g., McGaugh & Herz, 1972).
KeywordsRetrograde Amnesia Inhibitory Avoidance Electroconvulsive Shock Conditioned Emotional Response Inhibitory Avoidance Task
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