Conditioning pp 265-280 | Cite as

Activity of Neurons in Area 4 and in Area 5 of Monkey During Operant Conditioning of a Flexion Movement

  • Y. Burnod
  • B. Maton
  • J. Calvet
Part of the Advances in Behavioral Biology book series (ABBI, volume 26)


Present data concern changes of neuronal activity in Area 4 and Area 5 of macaca Speciosa, during shaping of a self initiated flexion movement of the elbow without sensory cues. Two behavioral changes occur during this period and are quantified:increase in the frequency of movements and change in the shape (amplitude, muscular contraction of biceps and triceps). The authors propose a model to quantify neuronal patterns whose changes are compared with the changes in behavior. Two sets of neurons are described, one more active with the flexion movement, the other active with the taking of the reward by the ipsilateral arm; there is an important spatial overlap between them. Neurons active both with conditioned movement and taking of the reward can show an enhancement of their activity when the first series of movements appear. An increase in the regularity of the conditioned movement corresponds to a balance between the two sets described. Cells whose activity is maximal with the conditioned movement show changes parallel with performance. During the sessions in which there is an increase in the accuracy of the movement, some cells show an increase in activity at the onset of the flexion movement.


Neuronal Activity Operant Conditioning Conditioning Session Flexion Movement Successive Movement 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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  1. Y. Bioulac and Y. Lamarre, 1979, Activity of postcentral cortical neurons of the monkey during conditioned movements of a deafferented limb, Brain Res., 172: 427.PubMedCrossRefGoogle Scholar
  2. E.V. Evarts, 1966, Pyramidal tract activity associated with a conditioned hand movement in the monkey, J. Neurophysiol., 29: 1011.PubMedGoogle Scholar
  3. E.V. Evarts, 1974, Gating of motor cortex reflexes by prior instruction, Brain Res., 74: 479.CrossRefGoogle Scholar
  4. E. Fetz and M.A. Baker, 1973, Operantly conditioned patterns of precentral unit activity and correlated response in adjacent cells and contralateral muscles, J. Neurophysiol. 36: 179.PubMedGoogle Scholar
  5. E.G. Jones, J.D. Coulder, and S.H.C. Hendry, 1978, Intracortical connectivity of architectonic fields in the somatic sensory, motor and parietal cortex of monkeys, J. Comp. Neur. 181: 291.Google Scholar
  6. W.A. MacKay, M.C. Kwan, J.T. Murphy, and Y.C. Wong, 1978, Responses to active and passive wrist rotation in Area 5 of awake monkeys, Neuroscience Letters 10: 235.PubMedCrossRefGoogle Scholar
  7. V.B. Mountcastle, J.C. Lynch, A. Georgopoulos, H. Sakata, and C. Acuna, 1975, Posterior parietal association cortex of the monkey:command functions for operations within extrapersonal space, J. Neurophysiol. 38 (4): 871.PubMedGoogle Scholar
  8. J. Olds, J.F. Disterhoft, M. Segal, C.L. Kornblith, and R. Hirsch, 1972, Learning centers of rat brain mapped by measuring letencies of conditioned unit responses, J. Neurophysiol. 35: 202.PubMedGoogle Scholar
  9. C.G. Phillips and R. Porter, 1977, “Corticospinal neurons: their role in movement”, Academic Press, London.Google Scholar
  10. H. Sakata, Y. Takaska, A. Karasawak, and H. Shubitani, 1973, Somatosensory properties of neurons in the superior parietal cortex (Area 5) of the rhesus monkey, Brain Res. 64: 85.PubMedCrossRefGoogle Scholar
  11. E.M. Schmidt, J.S. MacIntosch, L. Durelli, and J. Bak, 1978, Fine control of operantly conditioned firing patterns of percentral neurons, Exp. Neurology 61: 340.Google Scholar

Copyright information

© Springer Science+Business Media New York 1982

Authors and Affiliations

  • Y. Burnod
    • 1
  • B. Maton
    • 1
  • J. Calvet
    • 1
  1. 1.Hopital SalpetriereINSERMU 3 CNRSParisFrance

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