Effects of Chlorinated Paraffins on Some Drug-Metabolizing Enzymes in Rat Liver and in the Ames Test

  • J. Meijer
  • M. Rundgren
  • A. Åström
  • J. W. Depierre
  • A. Sundvall
  • U. Rannug
Part of the Advances in Experimental Medicine and Biology book series (AEMB)


Chlorinated paraffins (CP) consist of alkanes of the C10-C30 range with different degrees of chlorination. Commercially produced CP therefore consist of a variety of isomers with different chain lengths and chlorine content and a range or mean is given for each batch produced.


Liver Microsome Sodium Dodecyl Sulphate Epoxide Hydrolase Styrene Oxide Ames Test 
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Copyright information

© Springer Science+Business Media New York 1982

Authors and Affiliations

  • J. Meijer
    • 1
  • M. Rundgren
    • 1
  • A. Åström
    • 1
  • J. W. Depierre
    • 1
  • A. Sundvall
    • 2
  • U. Rannug
    • 2
  1. 1.Department of BiochemistryArrhenius Laboratory University of StockholmStockholmSweden
  2. 2.Environmental Toxicology UnitWallenberg Laboratory University of StockholmStockholmSweden

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