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Inhibition of Rat Hepatic Microsomal Epoxide Hydrase by Heavy- and Organometals in Vitro

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Biological Reactive Intermediates—II

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 136))

Abstract

Metal ions are capable of interacting with different groups of protein molecules. As a result of these interactions stabilization or destruction of the protein structure may take place (1). The enzymatic activities may be modified, ie. activated or inhibited (1).

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Author information

Authors and Affiliations

  1. Department of Physiology, University of Turku, Turku, Finland

    Max Georg Parkki

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  1. Max Georg Parkki
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Editor information

Editors and Affiliations

  1. Rutgers University, Piscataway, New Jersey, USA

    Robert Snyder , Charlotte M. Witmer  & Beatrice N. Engelsberg ,  & 

  2. Medical University of South Carolina, Charleston, South Carolina, USA

    David J. Jollow  & Stephen L. Longacre  & 

  3. University of Surrey, Guildford, Surrey, England

    Dennis V. Parke  & C. Gordon Gibson  & 

  4. Thomas Jefferson University, Philadelphia, Pennsylvania, USA

    James J. Kocsis  & George F. Kalf  & 

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Parkki, M.G. (1982). Inhibition of Rat Hepatic Microsomal Epoxide Hydrase by Heavy- and Organometals in Vitro. In: Snyder, R., et al. Biological Reactive Intermediates—II. Advances in Experimental Medicine and Biology, vol 136. Springer, New York, NY. https://doi.org/10.1007/978-1-4757-0674-1_54

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  • DOI: https://doi.org/10.1007/978-1-4757-0674-1_54

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  • Online ISBN: 978-1-4757-0674-1

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