Mechanism of the Luminescent Oxidation of Cypridina Luciferin

  • Osamu Shimomura
  • Frank H. Johnson


In an aqueous medium with Cypridina luciferase, or in an aprotic solvent without luciferase, the aerobic oxidation of Cypridina luciferin is accompanied by emission of light (1,2,3). The products of the luminescent oxidation have been reported as oxyluciferin and CO2 (4,5,6), although the oxyluciferin can be further converted to etioluciferin by acid or slowly by luciferase (4,7).


Keto Acid Tertiary Alcohol Bacterial Bioluminescence Blue Fluorescent Protein Glycine Derivative 
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Copyright information

© Springer Science+Business Media New York 1973

Authors and Affiliations

  • Osamu Shimomura
    • 1
  • Frank H. Johnson
    • 1
  1. 1.Biology DepartmentPrinceton UniversityPrincetonUSA

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