Hepatic and Metabolic Effects of Ethanol on Rhesus Monkeys

  • Boris H. Ruebner
  • Robert I. Krieger
  • Jeffrey L. Miller
  • Makepeace Tsao
  • Marie Rorvik
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 59)


Human alcoholics may suffer from a great variety of hepatic morphologic and biochemical abnormalities such as fatty liver, alcoholic hepatitis and cirrhosis. In addition, the metabolism of alcohol and of drugs is accelerated in human alcoholics (Shah,et al, 1972). The mechanisms of these changes are still disputed. Hepatic fatty change has been attributed to nutritional imbalance (Porta et al, 1970) and to a direct toxic effect of ethanol (Lieber et al, 1971). The mechanism of the accelerated metabolism of alcohol also remains uncertain.


Fatty Liver Rhesus Monkey Prussian Blue Chronic Ethanol Alcoholic Hepatitis 
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Copyright information

© Springer Science+Business Media New York 1975

Authors and Affiliations

  • Boris H. Ruebner
    • 1
  • Robert I. Krieger
    • 1
  • Jeffrey L. Miller
    • 1
  • Makepeace Tsao
    • 1
  • Marie Rorvik
    • 1
  1. 1.Departments of Pathology and Surgery, School of Medicine and Department of Environmental ToxicologyCollege of Agriculture, University of CaliforniaDavisUSA

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