Alcohol Withdrawal Convulsions in Genetically Different Populations of Mice

  • Dora B. Goldstein
  • Ryoko Kakihana
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 59)


The question whether alcoholism is inherited is a complex one. Some human populations have much higher rates of alcoholism than others. Genetic differences between populations might explain their alcoholism rates but it is equally likely that cultural habits determine the extent of drinking in a given population and thus secondarily account for the incidence of alcoholism. When the heritability of alcoholism has been examined by methods that rule out cultural differences, the results suggest that there is indeed a genetic component. Studies of twins (Kaij, 1960; Partanen et al, 1966) and of adopted sons of alcoholic biological parents (Schuckit, 1972; Goodwin et al, 1973) show a high incidence of alcoholism in relatives of alcoholics.


Inbred Strain Alcohol Withdrawal C57BL Mouse Blood Alcohol Level Vapor Chamber 
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Copyright information

© Springer Science+Business Media New York 1975

Authors and Affiliations

  • Dora B. Goldstein
    • 1
  • Ryoko Kakihana
    • 1
  1. 1.Departments of Pharmacology and PsychiatryStanford University School of MedicineStanfordUSA

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