Cyclic Nucleotides in the Central Nervous System

  • Kenneth A. Bonnet

Abstract

This chapter is intended to present perspectives on the role of cyclic nucleotides in central nervous system function and pathology. The coverage is representative rather than comprehensive and extends to July, 1980. The particular focus of the present chapter is on the cyclic nucleotides themselves. The synthesizing and degradative enzymes in the cyclic nucleotide systems and the protein kinases activated by the cyclic nucleotides in the central nervous system are the subjects of individual chapters of subsequent volumes of this series.

Keywords

Adenylate Cyclase Cyclic Nucleotide Rapid Freezing Protein Binding Assay Cyclic Nucleotide Level 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. 1.
    Siggins, G. R., 1979, Adv. Exp. Med. Biol. 116: 41–64.PubMedGoogle Scholar
  2. 2.
    Schmidt, M., Schmidt, D., and Robison, G., 1971, Science 173: 1142–1143.PubMedGoogle Scholar
  3. 3.
    Hutchkins, D., and Rodgers, K., 1970, Br. J. Pharmacol. 39: 9–25.Google Scholar
  4. 4.
    Mark, J., Godin, G.. and Mandel, P., 1963, J. Neurochem. 15: 141–143.Google Scholar
  5. 5.
    Lowry, O., Passonneau, J., Hasselberger, F., and Schultz, D., 1964, J. Biol. Chem. 239: 18–30.PubMedGoogle Scholar
  6. 6.
    Kakiuchi, S., and Rall, T. W., 1968, Mol. Pharmacol. 4: 379–388.PubMedGoogle Scholar
  7. 7.
    Stavinoha, W., Weintraub, S., and Modak, T., 1973, J. Neurochem. 20: 361–371.PubMedGoogle Scholar
  8. 8.
    Schmidt, M. J., Schmidt, D. E., and Robison. G. A., 1971, Science 173: 1142–1143.PubMedGoogle Scholar
  9. 9.
    Mao, C., Guidotti, A., and Costa, E., 1974, Mol. Pharmacol. 10: 736–745.Google Scholar
  10. 10.
    Balcom, G., Lenox, R. H., and Meyerhoff, J., 1975, J. Neurochem. 24: 609–613.PubMedGoogle Scholar
  11. 11.
    Lenox, R. H., Meyerhoff, J., Ghandi, O., and Wray, H., 1977, J. Cyclic Nucleotide Res. 3: 367–379.PubMedGoogle Scholar
  12. 12.
    Lenox, R. H., Balcom, G., and Meyerhoff, J., 1979, Neurosci. Abstr. 6: 788.Google Scholar
  13. 13.
    Butcher, R. W., and Butcher, S., 1976, Life Sci. 19: 1079–1087.PubMedGoogle Scholar
  14. 14.
    Biggio, G., and Guidotti, A., 1976, Brain Res. 107: 365–373.PubMedGoogle Scholar
  15. 15.
    Corda, M., Biggio, G., and Gessa, G., 1980, Brain Res. 188: 287–290.PubMedGoogle Scholar
  16. 16.
    Delapaz, R. L., Dickman, S. R., and Grosser, B. 1., 1975, Brain Res. 85: 171–175.PubMedGoogle Scholar
  17. 17.
    Dinnendahl, V., 1975, Brain Res. 100: 716–719.PubMedGoogle Scholar
  18. 18.
    Bonnet, K., 1975, Life Sci. 16: 1877–1882.PubMedGoogle Scholar
  19. 19.
    Steiner, A., Ferendelli, J., and Kipnis, D., 1972, J. Biol. Chem. 247: 1121–1124.PubMedGoogle Scholar
  20. 20.
    Cramer, H., Paul, M., Silbergold, S., and Forn, J., 1971, J. Neurochem. 18: 1605–1608.PubMedGoogle Scholar
  21. 21.
    Lenox, R., Brown, P., and Meyerhoff, J., 1979, Trends Neurosci. 2: 106–109.Google Scholar
  22. 22.
    Bonnet, K., Branchey, L., Friedhoff, A., and Ehrlich, Y., 1978, Life Sci. 22: 2003–2008.PubMedGoogle Scholar
  23. 23.
    Ehrlich, Y., Bonnet, K., Davis, L., and Brunngraber, F., 1979, Mechanisms Regulation and Special Functions of Protein Synthesis in Brain (S. Roberts, ed.), Plenum Press, New York, pp. 273–277.Google Scholar
  24. 24.
    Ehrlich, Y., Bonnet, K., Davis, L., and Brunngraber, E., 1978, Life Sci. 23: 137–145.PubMedGoogle Scholar
  25. 25.
    Bonnet, K. A., 1975, Life Sci. 16: 1877–1882.PubMedGoogle Scholar
  26. 26.
    Lust, W., Passonneau, J., and Veech, R., 1973, Science 181: 280–282.PubMedGoogle Scholar
  27. 27.
    Lenox, R., Meyerhoff, J., Ghandi, O., and Wray, H., 1977, J. Cyclic Nucleotide Res. 3: 367–379.PubMedGoogle Scholar
  28. 28.
    Schmidt, M., Schmidt, D., and Robison, G., 1971, Science 173: 1142–1143.PubMedGoogle Scholar
  29. 29.
    Veech, R., Harris, R., Veloso, D., and Veech, E., 1973, J. Neurochem. 20: 183–188.PubMedGoogle Scholar
  30. 30.
    Kilbride, P., and Ebrey, T., 1980, J. Gen. Physiol. 74: 415–426.Google Scholar
  31. 31.
    Palkovits, M., 1973, Brain Res. 59: 449–450.PubMedGoogle Scholar
  32. 32.
    Meurs, H., Kauffman, H., Koeter, G., and DeVries, K., 1980, Clin. Chim. Acta 106: 91–97.PubMedGoogle Scholar
  33. 33.
    Gilman, A., 1970, Proc. Natl. Acad. Sci. U.S.A. 67: 305–312.PubMedGoogle Scholar
  34. 34.
    Hughes, R., and Ayad, S., 1979, Clin. Chim. Acta 97: 197–204.PubMedGoogle Scholar
  35. 35.
    Vossenberg, J., 1979, J. Clin. Chem. Clin. Biochem. 17: 581–585.PubMedGoogle Scholar
  36. 36.
    Rosenberg, E., LaVallee, G., Weber, F., and Tucci, S., 1979, J. Histochem. Cytochem. 27: 913–923.PubMedGoogle Scholar
  37. 37.
    Daly, J., 1977, Cyclic Nucleotides in the Nervous System, Plenum Press, New York.Google Scholar
  38. 38.
    Bartfai, T., 1980, Curr. Topics Cell. Regal. 16: 225–269.Google Scholar
  39. 39.
    Rodbell, M., Lin, M. C., and Salomon, Y., 1974, J. Biol. Chem. 249: 59–65.PubMedGoogle Scholar
  40. 40.
    Rasmussen, H., and Goodwin, D. B. P., 1977, Physiol. Rev. 57: 421–509.PubMedGoogle Scholar
  41. 41.
    Hegstrand, L., Minneman, K., and Molinoff, P. B., 1979, J. Pharmacol. Exp. Ther. 210: 215–221.PubMedGoogle Scholar
  42. 42.
    Rodbell, M., Lin, M., Salomon, Y., and Londos, C., 1975, Adv. Cyclic Nucleotide Res. 5: 3–29.PubMedGoogle Scholar
  43. 43.
    Goldberg, N. D., and Haddox, M. K., 1977, Annu. Rev. Biochem. 46: 823–896.PubMedGoogle Scholar
  44. 44.
    Severin, E., Gulayaev, N., Bulargina, T., and Kochetkova, M., 1979, Adv. Enzyme Regal. 17: 251–282.Google Scholar
  45. 45.
    Mittal, C., Braughler, J., Ichihara, K., and Murad, F., 1980, Biochim. Biophys. Acta 585: 333–342.Google Scholar
  46. 46.
    Appelman, M. M., Thompson, W., and Russell, T., 1973, Adv. Cyclic Nucleotide Res. 3: 66–98.Google Scholar
  47. 47.
    Brostrom, C. O., and Wolff, D. J., 1976, Arch. Biochem. Biophys. 172: 301–311.PubMedGoogle Scholar
  48. 48.
    Ho, R. J., and Sutherland, E. W., 1975, Adv. Cyclic Nucleotide Res. 5: 533–548.PubMedGoogle Scholar
  49. 49.
    Cheung, W. Y., 1971, Biochim. Biophys. Acta 242: 395–409.PubMedGoogle Scholar
  50. 50.
    Davis, C. W., and Daly, J. W., 1980, Mol. Pharmacol. 17: 206–211.PubMedGoogle Scholar
  51. 51.
    Davis, C. W., and Daly, J. W., 1978, J. Biol. Chem. 253: 8683–8686.PubMedGoogle Scholar
  52. 52.
    Kant, G. J., Meyerhoff, J. L., and Lenox, R. H., 1979, Biochem. Pharmacol. 29: 369–373.Google Scholar
  53. 53.
    Schwabe, U., Miyake, M., Ohga, Y., and Daly, J. W., 1976, Mol. Pharmacol. 12: 900–910.PubMedGoogle Scholar
  54. 54.
    Smellie, F. W., Davis, C. W., Daly, J. W., and Well, J., 1979, Life Sci. 24: 2475–2480.PubMedGoogle Scholar
  55. 55.
    RaIl, T. W., 1978, Neuronal Information Transfer (A. Karlin, V. Tennyson, and H. Vogel, eds.), Academic Press, New York, pp. 323–338.Google Scholar
  56. 56.
    Smellie, F. W., Daly, J. W., and Wells, J. N., 1979, Life Sci. 25: 1917–1924.PubMedGoogle Scholar
  57. 57.
    Sutherland, E. W., and Rall, T. W., 1957, J. Am. Chem. Soc. 79: 3608.Google Scholar
  58. 58.
    Nathanson, J., 1977, Physiol. Rev. 57: 157–256.PubMedGoogle Scholar
  59. 59.
    Ahlquist, R. P., 1948, Am. J. Physiol. 153: 586–600.PubMedGoogle Scholar
  60. 60.
    Minneman, K. P., Dibner, M. D., Wolfe, B. B., and Molinoff, P. B., 1979, Science 204: 866–868.PubMedGoogle Scholar
  61. 61.
    Daly, J. W., Padgett, W., Nimitkitpaisan, Y., Creveling, C. R., Cantacuzene, D., Kirk, K. L., 1980, J. Pharmacol. Exp. Ther. 212: 382–389.PubMedGoogle Scholar
  62. 62.
    Haidamous, M., Kouyoumdjian, J., Briley, P., Gonnard, P., 1980, Eur. J. Pharmacol. 63: 287–294.PubMedGoogle Scholar
  63. 63.
    Daly, J. W., McNeal, E., Partington, C., Neuwirth, M., and Creveling, C. R., 1980, J. Neurochem. 35: 326–337.PubMedGoogle Scholar
  64. 64.
    Daly, J. W., McNeal, E. T., and Creveling, C. R., 1979, Histamine Receptors (T. O. Yellin, ed.), SP Medical and Scientific Books, New York, pp. 299–323.Google Scholar
  65. 65.
    Kanoff, P. O., and Greengard, P., 1979, Mol. Pharmacol. 15: 445–461.Google Scholar
  66. 66.
    Kebabian, J. W., and Calne, D. B., 1979, Nature 277: 93–96.PubMedGoogle Scholar
  67. 67.
    Weiss, B., Prozialeck, W., and Cimino, M., 1980, Adv. Cyclic Nucleotide Res. 12: 213–225.PubMedGoogle Scholar
  68. 68.
    Friedhoff, A. J., Bonnet, K. A., and Rosengarten, H., 1977, Res. Commun. Chem. Pathol. Pharmacol. 16: 411–423.PubMedGoogle Scholar
  69. 69.
    Pagel, J., Christian, S. T., Quayle, E. S., and Monti, J. A., 1976, Life Sci. 19: 819–824.PubMedGoogle Scholar
  70. 70.
    Mah, H., and Daly, J., 1976, Pharmacol. Res. Commun. 8: 65–79.PubMedGoogle Scholar
  71. 71.
    Traber, J., Reiser, G., Fischer, K., and Hamprecht, B., 1975, FEBS Lett. 52: 327–332.PubMedGoogle Scholar
  72. 72.
    Bonnet, K. A., 1979, Modulators, Mediators and Specifiers in Brain Function (Y. Ehrlich, J. Volavka, L. Davis, and E. Brunngraber, eds.), Plenum Press, New York, pp. 247–259.Google Scholar
  73. 73.
    Lambert, A., Nirenberg, M., and Klee, W. A., 1976, Proc. Natl. Acad. Sci. U.S.A. 73: 3165–3167.Google Scholar
  74. 74.
    Hamprecht, B., 1980, J. Neurochem. 33: 999–1005.Google Scholar
  75. 75.
    Ross, D. H., and Cardenas, H. L., 1980, Adv. Biochem. Psychopharmacol. 20: 301–317.Google Scholar
  76. 76.
    Bonnet, K. A., Branchey, L., Friedhoff, A. J., and Ehrlich, Y., 1978, Life Sci. 22: 2003–2008.PubMedGoogle Scholar
  77. 77.
    Kinscherf, D. A., Chang, M., Rubin, E., Schneider, D., and Ferendelli, J. A., 1976, J. Neurochem. 26: 527–530.PubMedGoogle Scholar
  78. 78.
    Ferendelli, J. A., Kinscherf, D., and Chang, M., 1973, Mol. Pharmacol. 9: 445–454.Google Scholar
  79. 79.
    Shimizu, H., Creveling, C. R., and Daly, J. W., 1970, Adv. Biochem. Psychopharmacol. 3: 135–154.PubMedGoogle Scholar
  80. 80.
    Ahnert, G., Glossmann, H., and Habermann, E., 1980, Arch. Pharmacol. 307: 151–157.Google Scholar
  81. 81.
    Lenox, R. H., Kant, G., and Meyerhoff, J. L., 1980, Life Sci. 26: 2201–2209.PubMedGoogle Scholar
  82. 82.
    Kebabian, J. W., Steiner, A. L., and Greengard, P., 1975, J. Pharmacol. Exp. Ther. 193: 474–488.PubMedGoogle Scholar
  83. 83.
    Daly, J. W., McNeal, E., and Creveling, C., 1979, Histamine Receptors (T. O. Yellin, ed.), SP Medical Books, New York, pp. 299–323.Google Scholar
  84. 84.
    Bartfai, T., Study, R. E., and Greengard, P., 1977, Cholinergie Mechanisms and Pharmacology (D. J. Jenden, ed.), Plenum Press, New York, p. 285.Google Scholar
  85. 85.
    Nathanson, N. M., Klein, N. L., and Nirenberg, M., 1978, Proc. Natl. Acad. Sci. U.S.A. 75: 1788–1791.PubMedGoogle Scholar
  86. 86.
    Haidamous, M., Kouyoumdjian, J., Briley, P., and Gonnard, P., 1980, Eur. J. Pharmacol. 63: 287–294.PubMedGoogle Scholar
  87. 87.
    Klee, W. A., and Nirenberg, M., 1974, Proc. Natl. Acad. Sci. U.S.A. 71: 3474–3477.PubMedGoogle Scholar
  88. 88.
    Watanabe, A. M., McConnaugh, M. M., Strawbridge, R. A., Fleming, J. W., Jones, L. A., and Besch, H. R., 1978, J. Biol. Chem. 253: 4833–4836.PubMedGoogle Scholar
  89. 89.
    Nikodijevic, O., Nikodijevic, B., Zinder, O., Yi, M., Guroff, G., and Pollard. H. B., 1976, Proc. Natl. Acad. Sci. U.S.A. 73: 771–774.PubMedGoogle Scholar
  90. 90.
    Westcott, K. R., LaPorte, D., and Storme, D. R., 1979, Proc. Natl. Acad. Sci. U.S.A. 76: 204–208.PubMedGoogle Scholar
  91. 91.
    Nathanson, J. A., and Bloom, F. E., 1975, Nature 255: 419–420.PubMedGoogle Scholar
  92. 92.
    LeMay, A., and Jurett, L., 1975, J. Cell Biol. 65: 39–50.PubMedGoogle Scholar
  93. 93.
    Walker, J. B., 1974, Biol. Psychiatry 8: 245–251.PubMedGoogle Scholar
  94. 94.
    Woolf, C. J., Willies, G. H., and Rosendorff, C., 1976, Naturwissenschaften 63: 94–95.PubMedGoogle Scholar
  95. 95.
    Miller, R. J., and Kelly, P. H., 1975, Nature 255: 163–166.PubMedGoogle Scholar
  96. 96.
    Blosser, J., and Appel, S., 1980, J. Biol. Chem. 255: 1235–1238.PubMedGoogle Scholar
  97. 97.
    Ehrlich, Y., 1979, Modulators, Mediators and Specifiers in Brain Function (Y. Ehrlich, J. Volavka, L. Davis, and E. Brunngraber, eds.), Plenum Press, New York, pp. 75–102.Google Scholar
  98. 98.
    Walter, U., Costa, M. R., Breakfield, X. O., and Greengard, P., 1979, Proc. Natl. Acad. Sci. U.S.A. 76: 3251–3255.PubMedGoogle Scholar
  99. 99.
    Gabibov, A., Kochetkov, S., Sashchenko, L., and Severin, E., 1979, Biochim. Biophys. Acta 569: 145–152.PubMedGoogle Scholar
  100. 100.
    Builder, S. E., Beavo, J. A., and Krebs, E. G., 1980, J. Biol. Chem. 255: 2350–2354.PubMedGoogle Scholar
  101. 101.
    Yagura, T., Sigman, C. C., Sturm, P., Reist, E., Johnson, H. I., and Miller, J., 1980, Biochem. Biophys. Res. Commun. 92: 463–467.PubMedGoogle Scholar
  102. 102.
    Hanbauer, I., and Guidotti, A., 1975, Arch. Pharmacol. 287: 213–217.Google Scholar
  103. 103.
    Lovenberg, W., Bruckwick, E., and Hanbauer, I., 1975, Proc. Natl. Acad. Sci. U.S.A. 72: 2955–2958.PubMedGoogle Scholar
  104. 104.
    Morgenroth, V. H., Hegstrand, L., Roth, R., and Greengard, P., 1975, J. Biol. Chem. 250: 1946–1948.PubMedGoogle Scholar
  105. 105.
    Joh, T., Park, D., and Reis, D., 1978, Proc. Natl. Acad. Sci. U.S.A. 75: 4744–4748.PubMedGoogle Scholar
  106. 106.
    Vulliet, P., Langan, T., and Weiner, N., 1980, Proc. Natl. Acad. Sci. U.S.A. 77: 92–96.PubMedGoogle Scholar
  107. 107.
    Costa, E., Chang, D., Guidotti, A., and Uzunov, P., 1975, Clinical Tools in Catecholamine Research (T. Malmfors, ed.), North Holland, Amsterdam, pp. 283–292.Google Scholar
  108. 108.
    Guidotti, A., Zivkovic, B., Pfeiffer, R., and Costa, E., 1973, Arch. Pharmacol. 278: 195–206.Google Scholar
  109. 109.
    Keen, P., and McLean, W., 1974, J. Neurochem. 22: 5–10.PubMedGoogle Scholar
  110. 110.
    Hamprecht, B., and Traber, J., 1974, FEBS Lett. 42: 221–226.PubMedGoogle Scholar
  111. 111.
    Kvetnansky, R., Gewirty, G., Weise, V., and Kopin, I., 1971, Endocrinology 89: 50–55.PubMedGoogle Scholar
  112. 112.
    Furmanski, P., Silverman, D. J., and Lukin, M., 1971, Nature 233: 413–415.PubMedGoogle Scholar
  113. 113.
    Werner, I., Peterson, G., and Shuster, L., 1971, J. Neurochem. 18: 141–151.PubMedGoogle Scholar
  114. 114.
    Prasad, K., and Mandel, 1972, Exp. Cell Res. 74: 532–534.PubMedGoogle Scholar
  115. 115.
    Schrier, B., and Shapiro, D., 1973, Exp. Cell Res. 80: 459–462.PubMedGoogle Scholar
  116. 116.
    Forn, J., Tagliamonte, A., Tagliamonte, P., and Gessa, G., 1972, Nature 237: 245–247.Google Scholar
  117. 117.
    Tagliamonte, A., Tagliamonte, P., Forn, J., Perez-Cruet, J., Krishna, G., and Gessa, G., 1970, J. Neurochem. 18: 1191–1196.Google Scholar
  118. 118.
    Axelrod, J., 1974, Science 184: 1341–1348.PubMedGoogle Scholar
  119. 119.
    Ichida, S., Yonehara, N., Watanabe, Y., and Yoshida, H., 1980, Brain Res. 192: 487–494.PubMedGoogle Scholar
  120. 120.
    Berridge, M., 1975, Adv. Cyclic Nucleotide Res. 6: 1–98.PubMedGoogle Scholar
  121. 121.
    Miyamoto, D., and Breckenridge, B., 1974, J. Gen. Physiol. 63: 609–624.Google Scholar
  122. 122.
    Wilson, D., 1974, J. Pharmacol. Exp. Ther. 188: 447–452.PubMedGoogle Scholar
  123. 123.
    DeLorenzo, R., Freedman, S., Yoke, W., and Mauren, S., 1979, Proc. Natl. Acad. Sci. U.S.A. 76: 1838–1842.PubMedGoogle Scholar
  124. 124.
    Ichida, S., Yonehara, N., Watanabe, Y., and Yoshida, H., 1980, Brain Res. 192: 487–494.PubMedGoogle Scholar
  125. 125.
    Pelayo, F., Dubocovich, M. L., and Langer. S. Z., 1978, Nature 274: 76–78.PubMedGoogle Scholar
  126. 126.
    Yonehara, N., Matsuda, T., Saito, K., and Yoshida, H., 1981, Brain Res. (in press).Google Scholar
  127. 127.
    Haidamous, M., Kouyoumdjian, J. C., Briley, P., and Gonnard, P., 1980, Eur. J. Pharmacol. 63: 287–294.PubMedGoogle Scholar
  128. 128.
    Greengard, P., 1979, Fed. Proc. 38: 2208–2217.PubMedGoogle Scholar
  129. 129.
    Wikberg, J., 1978, Nature 273: 164–166.PubMedGoogle Scholar
  130. 130.
    Starke, K., Endo, T., and Taube, H., 1975, Arch. Pharmacol. 291: 55–78.Google Scholar
  131. 131.
    Daszuta, A., Pons, F., and Cadhilac, J., 1979, Eur. J. Pharmacol. 56: 397–401.PubMedGoogle Scholar
  132. 132.
    Daly, J. W., 1977, Cyclic Nucleotides in the Nervous System, Plenum Press, New York, pp. 211.Google Scholar
  133. 133.
    Daniels, M., and Hamprecht, B.. 1974, J. Cell Biol. 63: 691–699.PubMedGoogle Scholar
  134. 134.
    Prasad, K., and Vernadakis, A., 1972, Exp. Cell Res. 70: 27–32.PubMedGoogle Scholar
  135. 135.
    Klier, G., Schubert, D., and Heinemann, S., 1975, Neurobiology 5: 1–7.PubMedGoogle Scholar
  136. 136.
    Prasad, K., Mandel, B., Waymire, J., Lees, G., Vernadakis, A., and Weiner, N., 1973, Nature 241: 117–119.Google Scholar
  137. 137.
    Clement-Courmier, Y., 1980, Adv. Biochem. Psychopharmacol. 22: 256–269.Google Scholar
  138. 138.
    Hamprecht, B., Joffe, B., and Philpott, G., 1973, FEBS Lett. 36: 193–198.PubMedGoogle Scholar
  139. 139.
    Furmanski, P., Silverman, D., and Lubin, M., 1971, Nature 233: 413–415.PubMedGoogle Scholar
  140. 140.
    Prasad, K., Kumar, S., Gilmer, K., and Vernadakis, A., 1973, Biochem. Biophys. Res. Commun. 50: 973–977.PubMedGoogle Scholar
  141. 141.
    Miller, R. J., and Ruddle, F., 1974, J. Cell Biol. 63: 295–299.PubMedGoogle Scholar
  142. 142.
    Glazer, R., and Schneider, F., 1975, J. Biol. Chem. 250: 2745–2749.PubMedGoogle Scholar
  143. 143.
    Thorner, M., 1977, J. Clin. Endocrinol. Metab. 6: 201–202.Google Scholar
  144. 144.
    Yancey, S., Weiner, R., and Schechter, J., 1980, Am. J. Anat. 157: 345–356.PubMedGoogle Scholar
  145. 145.
    Mathison, R., and Lederis, K., 1980, Endocrinology 106: 842–848.PubMedGoogle Scholar
  146. 146.
    Clark, R. B., Crumby, H., Davis, H., 1974, J. Physiol. (Lond.) 240: 493–504.Google Scholar
  147. 147.
    Woolf, C., Willies, G., and Rosendorff, C., 1976, Naturwissenschaften 63: 94–95.PubMedGoogle Scholar
  148. 148.
    Breckenridge, B., and Lisk, R., 1969, Proc. Soc. Exp. Biol. Med. 131: 934–935.PubMedGoogle Scholar
  149. 149.
    Rindi, G., Sciorelli, G., Poloni, M., and Acanfora, F., 1972, Experientia 28: 1047–1049.PubMedGoogle Scholar
  150. 150.
    Beani, L., Bianchi, C., and Bertelli, A., 1975, Pharmacol. Res. Commun. 7: 347–359.Google Scholar
  151. 151.
    Walland, A., 1975, Arch. Pharmacol. 290: 419–423.Google Scholar
  152. 152.
    Saxena, P., and Bahargava, K., 1974, Pharmacol. Res. Commun. 6: 347–355.PubMedGoogle Scholar
  153. 153.
    Gessa, G., Krishna, G., Forn, J., Tagliamonte, A., and Brodie, B., 1970, Adv. Biochem. Psychopharmacol. 3: 371–381.PubMedGoogle Scholar
  154. 154.
    Brus, R., Herman, Z., and Kostman, J., 1974, Pharmacol. Biochem. Behay. 2: 719–724.Google Scholar
  155. 155.
    Clark, R., Crumby, H., and Davis, H., 1974, J. Physiol. (Lond.) 240: 493–504.Google Scholar
  156. 156.
    Brus, R., Herman, Z., and Kostman, J., 1974, Pharmacol. Biochem. Behay. 2: 719–724.Google Scholar
  157. 157.
    Purpura, D., and Schoffer, R., 1974, Brain Res. 38: 179–181.Google Scholar
  158. 158.
    Henion, W. F., Sutherland, E., and Paternak, T., 1967, Biochim. Biophys. Acta 148: 106–113.PubMedGoogle Scholar
  159. 159.
    Vagaric, V., and Bedeslin, D., 1973, Brain Res. 57: 252–254.Google Scholar
  160. 160.
    Siggins, G., 1978, Neuronal Information Transfer (A. Karlin, V. Tennyson, and H. J. Vogel, eds.), Academic Press, New York, pp. 339–359.Google Scholar
  161. 161.
    Siggins, G., 1979, Modulators, Mediators and Specifiers in Brain Function (Y. Ehrlich, J. Volavka, L. Davis, and E. Brunngraber, eds.), Plenum Press, New York, pp. 41–64.Google Scholar
  162. 162.
    Bloom, F., 1979, Catecholamines: Basic and Clinical Frontiers (E. Usdin, I. Kopin, and J. Barchas, eds.), Pergamon Press, New York, pp. 609–618.Google Scholar
  163. 163.
    Nathanson, J., 1977, Physiol. Rev. 57: 157–256.PubMedGoogle Scholar
  164. 164.
    Butcher, R., and Sutherland, E., 1962, J. Biol. Chem. 240: 4515–4523.Google Scholar
  165. 165.
    Murad, F., 1973, Adv. Cyclic Nucleotide Res. 3: 355–383.PubMedGoogle Scholar
  166. 166.
    Aurbach, G., 1980, Adv. Cyclic Nucleotide Res. 12: 1–9.PubMedGoogle Scholar
  167. 167.
    Murad, F., 1973, Adv. Cyclic Nucleotide Res. 3: 355–383.PubMedGoogle Scholar
  168. 168.
    Ui, M., Honma, M., Kunitada, S., Okada, F., Ide, H., Hata, S., and Satoh. T.. 1980, Adv. Cyclic Nucleotide Res. 12: 25–35.PubMedGoogle Scholar
  169. 169.
    Honma, M., Satoh, T., Takezawa, J., and Ui, M., 1977, Biochem. Med. 18: 257–273.PubMedGoogle Scholar
  170. 170.
    Brooks, B., Engel, W., and Sode, J., 1977, Arch. Neurol. 34: 468–469.PubMedGoogle Scholar
  171. 171.
    Broadus, A., 1977, Adv. Cyclic Nucleotide Res. 8: 509–548.PubMedGoogle Scholar
  172. 172.
    Honma, M., and Ui, M., 1978, Eur. J. Pharmacol. 47: 1–10.PubMedGoogle Scholar
  173. 173.
    Cramer, H., Ng, L., and Chase, T., 1972, J. Neurochem. 19: 1601–1602.PubMedGoogle Scholar
  174. 174.
    Ebstein, R., Kara, T., and Belmaker, R., 1977, Acta Pharmacol. Toxicol. (Kbh.) 41: 80–83.Google Scholar
  175. 175.
    Belmaker, R., Zohar, J., and Ebstein, R., 1980, Adv. Cyclic Nucleot. Res. 12: 187–198.Google Scholar
  176. 176.
    Murad, F., and Pak, C., 1972, N. Engl. J. Med. 286: 1382–1387.PubMedGoogle Scholar
  177. 177.
    Pak, C., 1980, Adv. Cyclic Nucleotide Res. 12: 393–403.PubMedGoogle Scholar
  178. 178.
    Ebstein, R. P., Belmaker, R., Gunhaus, L., and Rimon, R., 1976, Nature 259: 411–413.PubMedGoogle Scholar
  179. 179.
    Guttler, R., Croxson, M., DeQuatro, V., Warren, D., Otis, C., and Niroloff, J., 1977, Metabolism 26: 1155–162.PubMedGoogle Scholar
  180. 180.
    Hamet, P., Franks, D., Adnot, S., and Coquil, J., 1980, Adv. Cyclic Nucleotide Res. 12: 11–23.PubMedGoogle Scholar
  181. 181.
    Abdullah, Y., and Hamadah, K., 1970, Lancet 1: 378–381.Google Scholar
  182. 182.
    Brown, B., Salway, J., Albano, J., Hublin, R., and Elkins, R., 1972, Br. J. Psychiatry 120: 405–408.PubMedGoogle Scholar
  183. 183.
    Belmaker, R., Kon, M., Ebstein, R., and DasBerg, H., 1981, Biol. Psychiatry 15: 3–8.Google Scholar
  184. 184.
    Robison, G. A., 1980, Adv. Cyclic Nucleotide Res. 12: 239–242.PubMedGoogle Scholar
  185. 185.
    Tsang, D., Lal, S., Sourkes, T., Ford, R., Aranoff, A., 1976, J. Neurol. Neurosurg. Psychiatry 39: 1186–1190.PubMedGoogle Scholar
  186. 186.
    Sebens, J., Koff, J., 1975, Exp. Neurol 46: 333–344.PubMedGoogle Scholar
  187. 187.
    Korf, J., Boer, P., and Felkes, D., 1976, Brain Res. 113: 551–561.PubMedGoogle Scholar
  188. 188.
    Kiessling, M., Lindl, T., and Cramer, H., 1975, Arch. Psychiatr. Nervenkr. 220: 325–333.PubMedGoogle Scholar
  189. 189.
    Belmaker, R., Ebstein, R., Biederman. J.. , R., , M., and van , H., 1978, Psychopharmacology 58: 307–310.PubMedGoogle Scholar
  190. 190.
    Post, R., Cramer, H., and Goodwin, F., 1977, Psychol. Med. 7: 599–605.PubMedGoogle Scholar
  191. 191.
    Kadouch, R., Belmaker, R., Ebstein, R., and Perez, L., 1977, Neuropsychobiology 3: 250–255.PubMedGoogle Scholar
  192. 192.
    Biederman, J., Rimon, R., Ebstein, R., Belmaker, R., and Davidson, J., 1977, Br. J. Psychiatry 130: 64–67.PubMedGoogle Scholar
  193. 193.
    Biederman, J., Rimon, R., Ebstein, R., Zohar, J., and Belmarker, R., 1976, Neuropsychobiology 2: 324–327.PubMedGoogle Scholar
  194. 194.
    Kebabian, J., Petzold, G., and Greengard, P., 1972, Proc. Natl. Acad. Sci. U.S.A. 69: 2145–2149.PubMedGoogle Scholar

Copyright information

© Springer Science+Business Media New York 1982

Authors and Affiliations

  • Kenneth A. Bonnet
    • 1
  1. 1.Department of PsychiatryNew York University School of MedicineNew YorkUSA

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