Papillomaviruses and Carcinogenic Progression II

The Mastomys natalensis Papillomavirus
  • Eberhard Amtmann
  • Klaus Wayss
Part of the The Viruses book series (VIRS)


Praomys (Mastomys) natalensis (A. Smith, 1834) is commonly called the multimammate mouse. The animal (Fig. 1), which is intermediate in size between mouse and rat, is one of the most common rodents in Africa south of the Sahara (Davis and Oettlé, 1958). In 1939, breeding of wild animals was started in South Africa (Davis and Oettlé, 1958) at the Med­ical Ecology Center, Johannesburg, in order to use them in plague research. In the following years, several times wild Mastomys were crossed with the laboratory colonies. In 1966, the Institute for Parasitology, Giessen, West Germany, started inbreeding chamois-colored mutants with red eyes. The ancestors of the partly inbred colony at the German Cancer Research Center, Heidelberg, were derived from the colony in Giessen in 1969.


Normal Skin Stomach Cancer Skin Tumor Spontaneous Tumor German Cancer Research 
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Copyright information

© Plenum Press, New York 1987

Authors and Affiliations

  • Eberhard Amtmann
    • 1
  • Klaus Wayss
    • 2
  1. 1.Institute for Virus ResearchGerman Cancer Research CenterHeidelbergFederal Republic of Germany
  2. 2.Institute for PathologyGerman Cancer Research CenterHeidelbergFederal Republic of Germany

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