The Expression of Papillomaviruses in Epithelial Cells

  • Lorne B. Taichman
  • Robert F. LaPorta
Part of the The Viruses book series (VIRS)


Papillomaviruses (PVs) are infectious DNA viruses capable of inducing benign and occasionally malignant growths specifically in keratinizing epithelia. A small number of PVs, such as bovine PV type 1 (BPV-1), are capable of inducing tumors of fibroblasts as well as of epithelial cells. However, only in epithelial cells does papillomavirus undergo vegetative replication. Infection of fibroblasts yields no progeny virus and is therefore a biological dead end.


Granular Layer Cornified Layer Cornified Envelope Keratin Protein Benign Papilloma 
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Copyright information

© Plenum Press, New York 1987

Authors and Affiliations

  • Lorne B. Taichman
    • 1
  • Robert F. LaPorta
    • 1
  1. 1.Department of Oral Biology and Pathology, School of Dental MedicineState University of New YorkStony BrookUSA

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