Skip to main content
SpringerLink
Log in

LSH Hamster Model of Syphilitic Infection and Transfer of Resistance with Immune T Cells

  • Chapter
Hamster Immune Responses in Infectious and Oncologic Diseases

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 134))

Abstract

The immunologic basis of host defense in syphilis has not been elucidated. The humoral immune response appears to afford only negligible protection. The disease progresses from a local lesion to secondary syphilis with 24% of patients developing relapsing secondary lesions despite the development of a vigorous antibody response. Passive immunization of rabbits or hamsters with immune serum (1–5) or immunoglobulin (6) has failed to prevent infection of animals with Treponema pallidum.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 84.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Perine, P.L. et al. Infect Immun 8 (1973) 787.

    PubMed  CAS  Google Scholar 

  2. Turner, T.B. et al. Johns Hopkins Med J 133 (1973) 241.

    PubMed  CAS  Google Scholar 

  3. Sepetjian, M. et al. Br J Vener Dis 49 (1973) 241.

    Google Scholar 

  4. Bishop, N.H.; Miller, J.N. J Immunol 117 (1976) 191.

    PubMed  CAS  Google Scholar 

  5. Schell, R.F. et al. J Infect Dis 140 (1979) 378.

    Article  PubMed  CAS  Google Scholar 

  6. Titus, R.G.; Weiser, R.S. J Infect Dis 140 (1979) 904.

    Article  PubMed  CAS  Google Scholar 

  7. Pavia, C.S. et al. Br J Vener Dis 54 (1978) 144.

    Google Scholar 

  8. Metzger, M.; Smogor, W. Arch Immunol Ther Exp (Warsz) 23 (1975) 625.

    CAS  Google Scholar 

  9. Baughn, R.E. et al. Infect Immun 17 (1977) 535.

    PubMed  CAS  Google Scholar 

  10. Hollander, D.H.; Turner, T.B. Am J Syph 38 (1954) 489.

    PubMed  CAS  Google Scholar 

  11. Miller, J.N. Spirochetes in Body Fluids and Tissues. Charles C. Thomas, Springfield, Illinois (1971).

    Google Scholar 

  12. Chan, J.K. et al. Infect Immun 26 (1979) 448.

    PubMed  CAS  Google Scholar 

  13. Schell, R.F. et al. J Infect Dis (1980) in press.

    Google Scholar 

  14. Blasecki, J.W.; Houston, K.J. Immunology 35 (1977) 1.

    Google Scholar 

  15. Dresser, D.W. In: Assays for Immunoglobulin-Secreting Cells, ed. Weir, pp. 28.1 — 28.25. Blackwell Scientific Publications, Oxford (1978).

    Google Scholar 

  16. Coe, J.E.; Green, I. J Natl Cancer Inst 54 (1975) 269.

    PubMed  CAS  Google Scholar 

  17. Wicher, K.; Jakubowski, A. Br J Vener Dis 40 (1964) 213.

    PubMed  CAS  Google Scholar 

  18. Bessemans, A.; DeMoor, A. Ann Inst Pasteur (Paris) 63 (1939) 569.

    Google Scholar 

  19. Gueft, B.; Rosahn, P.D. Am J Syph 32 (1948) 59.

    PubMed  CAS  Google Scholar 

  20. Schell, R.F. et al. Br J Vener Dis 51 (1975) 19.

    PubMed  CAS  Google Scholar 

  21. Schell, R.F. et al. Infect Immun (1980) in press.

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Medicine (Infectious Diseases), Hahnemann Medical College and Hospital, Philadelphia, PA, 19102, USA

    Ronald F. Schell, Jack L. LeFrock, John K. Chan & Omar Bagasra

Authors
  1. Ronald F. Schell
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Jack L. LeFrock
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. John K. Chan
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Omar Bagasra
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. The University of Texas Southwestern Medical School at Dallas, Dallas, Texas, USA

    J. Wayne Streilein , David A. Hart , Joan Stein-Streilein , William R. Duncan  & Rupert E. Billingham , , ,  & 

Rights and permissions

Reprints and permissions

Copyright information

© 1981 Plenum Press, New York

About this chapter

Cite this chapter

Schell, R.F., LeFrock, J.L., Chan, J.K., Bagasra, O. (1981). LSH Hamster Model of Syphilitic Infection and Transfer of Resistance with Immune T Cells. In: Wayne Streilein, J., Hart, D.A., Stein-Streilein, J., Duncan, W.R., Billingham, R.E. (eds) Hamster Immune Responses in Infectious and Oncologic Diseases. Advances in Experimental Medicine and Biology, vol 134. Springer, Boston, MA. https://doi.org/10.1007/978-1-4757-0495-2_26

Download citation

  • DOI: https://doi.org/10.1007/978-1-4757-0495-2_26

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4757-0497-6

  • Online ISBN: 978-1-4757-0495-2

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics

Search

Navigation