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Current Approaches to Therapy pp 313–373Cite as

Immunology and Immunotherapy of Human Breast Cancer

Recent Developments and Prospects for the Future

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Abstract

The discovery of tumor-specific antigens and tumor-specific immune responses in both animals and humans with malignant disease has increased understanding of the host defense mechanisms in the etiology and pathogenesis of cancer. However, before these tumor-specific immunological phenomena were clearly documented in man, it was strongly suspected that host defense mechanisms or their failure played a role in the etiology and pathogenesis of tumors. As these tumor-specific immune mechanisms were discovered in man, the concept of immunological surveillance was developed.(1)

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Authors and Affiliations

  1. Departments of Developmental Therapeutics, M. D. Anderson Hospital and Tumor Institute, University of Texas System Cancer Center, Houston, Texas, USA

    Jordan U. Gutterman, Giora M. Mavligit & Evan M. Hersh

  2. Departments of Medicine, M. D. Anderson Hospital and Tumor Institute, University of Texas System Cancer Center, Houston, Texas, USA

    Gabriel Hortobagyi & George Blumenschein

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  1. Jordan U. Gutterman
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  2. Giora M. Mavligit
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  3. Evan M. Hersh
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  1. University of Texas Health Science Center, San Antonio, Texas, USA

    William L. McGuire M.D.

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Gutterman, J.U., Mavligit, G.M., Hersh, E.M., Hortobagyi, G., Blumenschein, G. (1977). Immunology and Immunotherapy of Human Breast Cancer. In: McGuire, W.L. (eds) Current Approaches to Therapy. Springer, Boston, MA. https://doi.org/10.1007/978-1-4757-0480-8_7

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