Abstract
Several strains of murine coronavirus are able to induce a demyelinative disease in laboratory animals. The disease is characterized by a chronic course with relapses after the initial phase of acute encephalitis (Herdon et al., 1975; Holmes et al., 1980). Recently a coronavirus has also been implicated in human demyelin-ative disease, multiple sclerosis (Burks et al., 1980). In order to determine whether a coronavirus etiology for MS could be demonstrated in analogy to the role of measles virus in SSPE, we have studied the occurrence of coronavirus antibodies in two collections of clinical material.
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© 1981 Springer Science+Business Media New York
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Leinikki, P.O., Holmes, K.V., Shekarchi, I., Iivanainen, M., Madden, D., Sever, J.L. (1981). Coronavirus Antibodies in Patients with Multiple Sclerosis. In: ter Meulen, V., Siddell, S., Wege, H. (eds) Biochemistry and Biology of Coronaviruses. Advances in Experimental Medicine and Biology, vol 142. Springer, Boston, MA. https://doi.org/10.1007/978-1-4757-0456-3_26
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DOI: https://doi.org/10.1007/978-1-4757-0456-3_26
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