Abstract
It is gratifying the see the effort and attention given here to the issue of evaluating atherosclerotic lesions, especially atherosclerosis in living persons. Pathologists who have examined the arteries of autopsied persons for many years have longed for the opportunity to observe the movement of the process. In attempts to describe that movement, we have had to reconstruct the process by measuring various qualities of the lesions in large numbers of autopsied persons, and arranging the values in age sequence.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Katz, S.S., 1981, The lipids of grossly normal human aortic intima from birth to old age. J. Biol. Chem. 23:12275–12280.
Libby, P., Warner, S.J.C., and Friedman, G.B., 1988, Interleukin-1: a mitogen for human vascular smooth muscle cells that induces the release of growth inhibitory prostanoids, J. Clin. Invest. 88:487–498.
Libby, P., Salomon, R.N., Payne, D.D., Schoen, F.J., and Pober, J.S., 1989, Functions of vascular wall cells related to the development of transplantation-associated coronary arteriosclerosis. Transplantation Proc. 21:3677–3684.
McGill, H.C., Jr., 1988, The pathogenesis of atherosclerosis. Clin. Chem. 33:833–839.
McGill, H.C., Jr., Geer, J.C., and Strong, J.P., 1963, Natural history of human atherosclerotic lesions, in “Atherosclerosis and Its Origin,” M. Sandler and G.H. Bourne, eds. Academic Press, New York.
Melnick, J.L., Adam, E., and DeBakey, M.E., 1990, Possible role of cytomegalovirus in atherogenesis. JAMA 263:2204–2207.
Pober, J.S. and Cotran, R.S., 1990. Cytokines and endothelial cell biology. Physiol. Rev. 70:427–451.
Ross, R., Masuda, J., Raines, E.W., Gown, A.M., Katsuda, S., Sasahara, M., Maiden, L.T., Masuko, H., and Sato, H., 1990, Localization of PDGF-B protein in macrophages in all phases of atherogenesis. Science 248:1009–1012.
Stary, H.C., 1989, Evolution and progression of atherosclerotic lesions in coronary arteries of children and young adults. Arteriosclerosis (Supp. I) 9:1–19-1–32.
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1991 Plenum Press, New York
About this chapter
Cite this chapter
McGill, H.C. (1991). Atherosclerosis: A Moving Target Key Note Presentation. In: Wissler, R.W., Bond, M.G., Mercuri, M., Tanganelli, P., Weber, G., Friedman, G. (eds) Atherosclerotic Plaques. Nato ASI Series, vol 219. Springer, New York, NY. https://doi.org/10.1007/978-1-4757-0438-9_1
Download citation
DOI: https://doi.org/10.1007/978-1-4757-0438-9_1
Publisher Name: Springer, New York, NY
Print ISBN: 978-1-4757-0440-2
Online ISBN: 978-1-4757-0438-9
eBook Packages: Springer Book Archive