Skip to main content

Drug Therapy as an Aspect of Ecological Genetics

  • Chapter
  • 218 Accesses

Abstract

Human beings have been subjected to many changes in their environment in the last century and most of these cannot be accurately defined and quantified. However, a fairly recent one which can be studied with some precision relates to the fact that about half the population now consumes some type of drug medication more or less regularly.

This is a preview of subscription content, log in via an institution.

Buying options

Chapter
USD   29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD   84.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD   109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Learn about institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  • Armaly M.F. (1963a) Effect of corticosteroids on intraocular pressure and fluid dynamics I the effect of dexamethasone in the normal eye. Archs. Ophthal. N. Y. 70, 482–491.

    Article  CAS  Google Scholar 

  • Armaly M.F. (1963b) Effect of corticosteroids on intraocular pressure and fluid dynamics. II the effect of dexamethasone in the glaucomatous eye. Archs Ophthal N. Y. 70, 492–499.

    Article  CAS  Google Scholar 

  • Armaly M.F. (1965) Statistical attributes of the steroid hypertensive response in the clinically normal eye. I the demonstration of three levels of response. Invest. Ophthal. 4, 187–197.

    PubMed  CAS  Google Scholar 

  • Armaly M.F. (1966a) Dexamethasone ocular hypertension in the clinically normal eye. II The untreated eye outflow facility and concentration. Archs. Ophthal. N. Y. 75, 776–782.

    Article  CAS  Google Scholar 

  • Armaly M.F. (1966b) The heritable nature of dexamethasone-induced ocular hypertension. Archs. Ophthal. N. Y. 75, 32–35.

    Article  CAS  Google Scholar 

  • Armaly M.F. (1967a) Inheritance of dexamethasone hypertension and glaucoma. Archs Ophthal. N. Y. 77, 747–751.

    Article  CAS  Google Scholar 

  • Armaly M.F. (1967b) The genetic determination of ocular pressure in the normal eye. Archs Ophthal. N. Y. 78, 187–192.

    Article  CAS  Google Scholar 

  • Armaly M.F. (1967c) Dexamethasone ocular hypertension and eosinopenia and glucose tolerance test. Archs Ophthal. N. Y. 78, 193–197.

    Article  CAS  Google Scholar 

  • Armaly M.F. (1968) Genetic factors related to glaucoma. Ann. N.Y. Acad. Sci. 151, 861–875.

    Article  CAS  PubMed  Google Scholar 

  • Armaly M.F., Montstavicius B.F. & Sayegh R.E. (1968) Ocular pressure and aqueous outflow facility in siblings. Archs Ophthal. N. Y. 80, 350–360.

    Article  Google Scholar 

  • Armstrong J.R., Daily R.K., Dobson H.H. & Girard L.J. (1960) The incidence of glaucoma in diabetes mellitus. Am. J. Ophthal. 50, 55–63.

    Article  CAS  PubMed  Google Scholar 

  • Becker B. & Mills D.W. (1963) Corticosteroids and intraocular pressure. Archs Ophthal N. Y. 70, 500–507.

    Article  CAS  Google Scholar 

  • Becker B. (1964) The effect of topical corticosteroids in secondary glaucomas. Archs Ophthal N. Y. 72, 769–771.

    Article  CAS  Google Scholar 

  • Becker B. & Hahn K. A. (1964) Topical corticosteroids and heredity in primary open angle glaucoma. Am. J. Ophthal 57, 543–551.

    Article  CAS  PubMed  Google Scholar 

  • Becker B., Bresnick G., Chevrette L., Kolker A.E., Oaks M. & Cibis M. (1966) Intraocular pressure and its response to topical corticosteroids in diabetics. Archs Ophthal N. Y. 76, 477–483.

    Article  CAS  Google Scholar 

  • Becker B. & Ramsey C.K. (1970) Plasma Cortisol and the intraocular pressure response to topical corticosteroids. Am. J. Ophthal. 69, 999–1002.

    Article  CAS  PubMed  Google Scholar 

  • Brück H., Fearnley M.E., Meanock I. & Patley H. (1954) Phenylbutazone therapy: relation between the toxic and therapeutic effects and the blood level. Lancet I, 225–228.

    Article  Google Scholar 

  • Chrishansson J. (1961) Intraocular pressure in diabetes mellitus. Acta ophthal 39, 155.

    Article  Google Scholar 

  • Ford E.B. (1965) Genetic Polymorphism, p. 87. Faber and Faber, London.

    Google Scholar 

  • Fouts J.R. (1961) The metabolism of drugs by subfractions of hepatic microsomes. Biochem. biophys. Res. Commun. 6, 373–378.

    Article  CAS  PubMed  Google Scholar 

  • François J. (1961) Glaucome apparemment simple secondaire à la cortisonotheràpie locale. Ophthalmologic, Basel 142, 517–523.

    Google Scholar 

  • Galton F. (1889) Natural Inheritance. Macmillan, London.

    Book  Google Scholar 

  • Goldmann H. (1962) Cortisone glaucoma. Archs Ophthal. N. Y. 68, 621–626.

    Article  CAS  Google Scholar 

  • Grant W.M. (1964) Glaucoma Research Conference. Am. J. Ophthal 58, 1065.

    Article  Google Scholar 

  • Harris H. (1966) Enzyme polymorphisms in Man. Proc. R. Soc. B 164, 298–310.

    Article  CAS  Google Scholar 

  • Harris H. (1969) Genes and Isozymes. Proc. R. Soc. B174, 1–31.

    Article  Google Scholar 

  • Levene R.Z. & Schwartz B. (1968) Depression of plasma Cortisol and the steroid ocular pressure response. Archs Ophthal N. Y. 80, 461–466.

    Article  CAS  Google Scholar 

  • Levi A. J., Sherlock S. & Walker D. (1968) Phenylbutazone and isoniazid metabolism in patients with liver disease in relation to previous drug therapy. Lancet 1, 1275–1279.

    Article  CAS  PubMed  Google Scholar 

  • Robson J.M. & Stacey R.S. (1968) Recent advances in pharmacology; 4th edn., p. 34. Churchill, London.

    Google Scholar 

  • Rosenbaum L.J., Alton E. & Becker B. (1970) Dexamethasone testing in Southwestern Indians. Invest. Ophthal. 9, 325–330.

    PubMed  CAS  Google Scholar 

  • Safir A., Paulsen E.P. & Klayman J. (1964) Elevated intraocular pressure in diabetic children. Diabetes 13, 161–163.

    Article  CAS  PubMed  Google Scholar 

  • Stern J.J. (1953) Acute glaucoma during cortisone therapy. Am. J. Ophthal 36, 389–390.

    Article  CAS  PubMed  Google Scholar 

  • Trevor-Roper P.D. (1962) Ophthalmology. A Textbook for Diploma Students, p. 512. Lloyd-Luke, London.

    Google Scholar 

  • Vesell E.S. & Page J.G. (1968) Genetic control of drug levels in Man: phenylbutazone. Science 159, 1479–1480.

    Article  CAS  PubMed  Google Scholar 

  • Whittaker J. W. & Evans D. A.P. (1970) Genetic control of phenylbutazone metabolism in Man. Br. med. J. 4, 323–328.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

Download references

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 1971 Blackwell Scientific Publications

About this chapter

Cite this chapter

Evans, D.A.P. (1971). Drug Therapy as an Aspect of Ecological Genetics. In: Creed, R. (eds) Ecological Genetics and Evolution. Springer, New York, NY. https://doi.org/10.1007/978-1-4757-0432-7_18

Download citation

  • DOI: https://doi.org/10.1007/978-1-4757-0432-7_18

  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-1-4757-0434-1

  • Online ISBN: 978-1-4757-0432-7

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics