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Bioactive Polymeric Systems pp 143–150Cite as

Hydrogels for Controlled Drug Release

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Abstract

Hydrogels have been investigated for use in controlled-release drug delivery systems. Hydrogels show superior biocompatibility and permeation of both hydrophobic and hydrophilic drugs depending on the combination of copolymers. Drug diffusion through hydrogels depends on the hydrogel nature, mainly the percentage of cross-linking agents and hydrogel water content. Various devices designed with hydrogels are discussed in this chapter: reservoir systems, drug-dissolved monoliths, drug-dispersed monoliths, monolith devices with barrier layers, and novel delivery systems.

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Author information

Authors and Affiliations

  1. Department of Pharmaceutics, University of Utah, Salt Lake City, UT, 84112, USA

    Sung Wan Kim

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  1. Sung Wan Kim
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Editor information

Editors and Affiliations

  1. Youngstown State University, Youngstown, Ohio, USA

    Charles G. Gebelein

  2. Wright State University, Dayton, Ohio, USA

    Charles E. Carraher Jr.

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© 1985 Plenum Press, New York

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Kim, S.W. (1985). Hydrogels for Controlled Drug Release. In: Gebelein, C.G., Carraher, C.E. (eds) Bioactive Polymeric Systems. Springer, Boston, MA. https://doi.org/10.1007/978-1-4757-0405-1_6

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  • DOI: https://doi.org/10.1007/978-1-4757-0405-1_6

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4757-0407-5

  • Online ISBN: 978-1-4757-0405-1

  • eBook Packages: Springer Book Archive

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