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Microcirculation in Myocardium and Cerebral Cortex

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Heart Perfusion, Energetics, and Ischemia

Part of the book series: NATO Advanced Science Institutes Series ((NSSA,volume 62))

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Abstract

The cerebral microcirculation has been studied by a variety of methods. Most of the early findings were based on histological observations. Craigie (1921) studied the vascularity of the cerebral cortex of the rat with microscopic techniques and Florey (1925) stimulated by Sherrington’s observations, used Indian ink injections to outline cerebral microcirculation. Dunning and Wolfe (1937) injected Berlin blue, and by histological observations determined the vascularity of the parietal cortex. Using radiographic as well as tissue transparency, Rowbotham (1967) observed blood supply of the cerebral hemisphere and the white matter. Haswegawa (1967) by metallic impregnation, discovered precapillary thoroughfare channels in the cerebral cortex.

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References

  • BAYLISS, W.M. (1902): On the local action of the arterial wall to changes of internal pressure. J. Physiol. 28: 220–231.

    Google Scholar 

  • BING, R.J., and CHANG, B.L. (1982): Advances in Experimental Medicine and Biology. J.J. Spitzer, Plenum Press, New York, in press.

    Google Scholar 

  • BOURDEAU-MARTINI, J., and HONIG, C.R. (1973): Control of coronary intercapillary distance: Effect of arterial PCO2 and pH. Microvasc. Res. 6: 286–296.

    Article  Google Scholar 

  • CHAMBERS, R., and ZWEIFACH, B.W. (1946): Functional activity of the blood capillary bed, with special reference to visceral tissue. Ann. NY. Acad. Sci. 46:683.

    Article  Google Scholar 

  • CHANG, B.L., YAMAKAWA, T., NUCCIO, J., PACE, R., and BING, R.J. (1982): Microcirculation of left atrial muscle, cerebral cortex and mesentery of the cat. Circ. Res. 50: 240–249.

    Google Scholar 

  • CRAIGIE, E.H. (1921): The vascularity of the cerebral cortex of the Albino rat. J. Comp. Neurol. 33:193.

    Article  Google Scholar 

  • DUNNING, H.S., and WOLFF, H.G. (1937): The relative vascularity of various parts of the central and peripheral nervous system of the cat and its relation to function. J. Comp. Neurol. 67: 433–450.

    Article  Google Scholar 

  • EDVINSSON, L., and MACKENZIE, E.T. (1977): Amine mechanisms in the cerebral circulation. Pharmacol. Reviews 28: 275–348.

    Google Scholar 

  • FLOREY, H. (1925): Microscopical observations on the circulation of the blood in the cerebral cortex. Brain 48: 43–64.

    Article  Google Scholar 

  • GILMAN, A.G., GOODMAN, L.S., and GILMAN, A. (1980): The Pharmacological Basis of Therapeutics, ed 6. New York, Macmillan Publishing Co.

    Google Scholar 

  • HASEGAWA, T., RAVENS, J.R., and TOOLE, J.F. (1967): Precapillary arteriovenous anastomoses. Arch. Neurol. 16: 217–224.

    Article  Google Scholar 

  • HERNANDEX, M.J., BRENNAN, R.W., and BOWMAN, G.S. (1978): Cerebral blood flow autoregulation in the rat. Stroke 9: 150–155.

    Article  Google Scholar 

  • KALININA, M.K., and KEVKOVICH, Yu. I., IVANOV, K.P., and TRUSOVA, V.K. (1976): Blood flow velocity in cerebral cortex capillaries (microcinephotographic study), Dokl. Akad. Nauk. S.S.S.R., 226: 230–233.

    Google Scholar 

  • KONTOS, H.A., WEI, E.P., RAPER, A.J., and PATTERSON, J.L. (1977): Local mechanism of CO2 action on cat pial arterioles. Stroke 8: 226–229.

    Article  Google Scholar 

  • LASSEN, N.A., and CHRISTENSEN, M.S. (1976): Physiology of cerebral blood flow. Brit. J. Anaesth. 48: 719–734.

    Article  Google Scholar 

  • LUBBERS, D.W. (1976): Quantitative measurement and description of oxygen supply to the tissue. In: Oxygen and Physiological Function. F.F. Jobsis (Ed.). Dallas, Professional Information Library, pp. 254–274.

    Google Scholar 

  • MA, Y.P., KOO, A., KWAN, H.C., and CHENG, K.K. (1974): On-line measurement of the dynamic velocity of erythrocytes in the cerebral microvessels in the rat. Microvasc. Res. 8:1–13.

    Article  Google Scholar 

  • MACKENZIE, E.T., STRANDGAARD, S., GRAHAM, D.I., JONES, J.V., HARPER, A.M., and FARRAR, J.K. (1976): Effects of acutely induced hyper-tension in cats on pial arteriolar caliber, local cerebral blood flow, and the blood-brain barrier. Circ. Res. 39: 33–41.

    Google Scholar 

  • MCDOWALL, D.G. (1965): The effects of general anaesthetics on cerebral blood flow and cerebral metabolism. Brit. J. Anaesth. 37: 236–245.

    Article  Google Scholar 

  • MCHEDLISHVILI, G.I., NIKOLAISHVILI, L.S., and ANITA, R.V. (1976): Are the pial arterial responses dependent on the direct effect of intravascular pressure and extravascular and intravascular PO2, PCO2 and pH Microvasc. Res. 10: 298–311.

    Article  Google Scholar 

  • OPITZ, E., and SCHNEIDER, M. (1950): Uber die Sauerstoffversorgung des Gehirns und den Mechanismus von Mangelwirkungen. Ergeb. Physiol. 4: 126–203.

    Google Scholar 

  • PAWLIK, G., RACKL, A., and BING, R.J. (1981): Quantitative capillary topography and blood flow in the cerebral cortex of cats: an in vivo microscopic study. Brain. Res. 208: 35–58.

    Article  Google Scholar 

  • PIERCE, E.C., LANEITSEN, C.J., DEUTSCH, S., CHASE, P.E., LINDE, H.W., DRIPPS, R.D., and PIERCE, H.L. (1962): Cerebral circulation and metabolism during tiopental anaesthetic and hyperventilation in man. J. Clinc. Invest. 41: 1664–1671.

    Article  Google Scholar 

  • REBATEL, F. (1872): Recherches experimentales sur la circulation dans les arteres coronaires. Theses (288), Paris. Quoted from R.J. Bing: Coronary circulation and cardiac metabolism. In Circulation of the Blood: Men and Ideas, A.P. Fishman and D.W. Richards. (Eds.). New York, Oxford University Press. 1964, p. 235.

    Google Scholar 

  • REIVICH, M. (1974): Brain disfunction in metabolic disorders. Res. Nerv. Ment. Dis. 53: 125–140.

    Google Scholar 

  • ROSENBLUM, W.I., and KONTOS, H.A. (1974): The importance and relevance of studies of the pial microcirculation. Stroke 5: 425–428.

    Article  Google Scholar 

  • ROTH, J.A., GREENFIELD, A.J., KAIHARA, S., and WAGNER, H.H. J.R., (1970): Total and regional cerebral blood flow in unanesthetized dogs. Am. J. Physiol. 219: 96–101.

    Google Scholar 

  • ROWBOTHAM, G.F., and LITTER, E. (1965): Circulation of the cerebral hemispheres. Brit. J. Surg., 52:8.

    Article  Google Scholar 

  • SATO, M., NAGAO, T., YAMAGUCHI, I., NAKAJIMA, H., and KIYOMOTO, A. (1971): Pharmacological studies on a new 1,5 — Benzothiazepine derivative. (CRD-401). Arzneim. Forsch. (Drug-Res) 21: 1338–1343.

    Google Scholar 

  • SOKOKOFF, L. (1977): Relation between physiological function and energy metabolism in the central nervous system. J. Neurochem. 29: 13–26.

    Article  Google Scholar 

  • TILLICH, G., MENDOZA, L., WAYLAND, H. and BING, R.J. (1971): Studies of the coronary microcirculation of the cat. Am. J. Cardiol. 27: 93–98.

    Article  Google Scholar 

  • TILLMANNS, H., IKEDA, S., HANSEN, H., SARMA, J.S.M., FAUVEL, J.M. and BING, R.J. (1974): Microcircultion in the ventricle of the dog and turtle. Circ. Res. 34: 561–569.

    Google Scholar 

  • UNDERWOOD, E.E. (1970): Quantitative Stereology. Addison-Wesley, Reading, Mass.

    Google Scholar 

  • WOLLMAN, H., ALEXANDER, C., COHEN, P.J., SMITH, T.C., CHASE, P.E., and van der MOTEN, R. (1965): Cerebral circulation during general anesthesia and hyperventilation in man. Anesth. 26: 329–334.

    Article  Google Scholar 

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© 1983 Plenum Press, New York

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Bing, R.J., Chang, BL. (1983). Microcirculation in Myocardium and Cerebral Cortex. In: Dintenfass, L., Julian, D.G., Seaman, G.V.F. (eds) Heart Perfusion, Energetics, and Ischemia. NATO Advanced Science Institutes Series, vol 62. Springer, Boston, MA. https://doi.org/10.1007/978-1-4757-0393-1_8

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  • DOI: https://doi.org/10.1007/978-1-4757-0393-1_8

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4757-0395-5

  • Online ISBN: 978-1-4757-0393-1

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