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Thermodynamics and Cardiac Energetics

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Heart Perfusion, Energetics, and Ischemia

Part of the book series: NATO Advanced Science Institutes Series ((NSSA,volume 62))

Abstract

It would be inappropriate in this article to try and consider more than elementary aspects of thermodynamics as it applies to biological systems. The standard work, of particular interest to muscle physiologists, is that of Wilkie (1960) but less detailed accounts, biased towards an understanding of cardiac energetics, will be found in Gibbs (1974) and Gibbs and Chapman (1979a): there is also a good discussion of the concept of muscular efficiency by Wilkie (1974). An interesting book on cellular energy metabolism by Atkinson (1977) has a very clear appendix on biological thermodynamics.

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References

  • ALPERT, N.R., and MULIERE, L.A. (1982): Increased myothermal economy of isometric force generation in compensated cardiac hypertrophy induced by pulmonary artery constriction in rabbit. A characterization of heat liberation in normal and hypertropied right ventricular papillary muscles. Circ. Res. (In press).

    Google Scholar 

  • ARNOLD, G. and LOCHNER, W. (1965): Die Temperaturabhangigkeit des Sauerstoffverbrauches stillgestellter, kunstlichperfundierter Warmbluterherzen zwischen 34° and 4°C. Pflugers Archiv. 284: 169–175.

    Article  Google Scholar 

  • ATKINSON, D.E. (1977): Cellular Energy Metabolism and Its Regulation. pp. 239–263, Academic Press, New York.

    Google Scholar 

  • AZZONE, G.F., POZZAN, T., MASSARI, S., and BRAGADIN, M. (1978): Proton electrochemical gradient and rate of controlled respiration in mitochondria. Biochimica et biophysica acta 501: 97–112.

    Google Scholar 

  • BARANY, M. (1967): ATPase activity of myosin correlated with speed of muscle shortening. J. Gen. Physiol. 50: 197–216.

    Article  Google Scholar 

  • BASSINGTHWAITHE, J.B., and REUTER, H. (1972): Calcium movements and excitation-contraction coupling in cardiac cells. In: Electrical Phenomena in the Heart. pp. 354–396, de Mello, W.C. (ed.) Academic Press, New York.

    Google Scholar 

  • CHALLONER, D.R. (1968): Respiration in myocardium. Nature 217: 78–79.

    Article  Google Scholar 

  • CHAPMAN, J.B. (1983): Heat Production. In: Cardiac Metabolism, Drake, A.J. and Noble, M.I.M. (eds.) Wiley, Chichester (In press).

    Google Scholar 

  • CHAPMAN, J.B., and GIBBS, C.L. (1972): An energetic model of muscle contraction. Biophys. J. 12: 227–236.

    Article  Google Scholar 

  • CHAPMAN, J.B., and GIBBS, C.L. (1974): The effect of metabolic substrate on mechanical activity and heat production in papillary muscle. Cardiovas. Res. 8: 656–667.

    Article  Google Scholar 

  • CHAPMAN, J.B., GIBBS, C.L. and GIBSON, W.R. (1970): Effects of calcium and sodium on cardiac contractility and heat production in rabbit papillary muscle. Circ. Res. 27: 601–610.

    Google Scholar 

  • CHAPMAN, J.B., GIBBS, C.L. and LOISELLE, D.S. (1982): Myothermic, Polarographie, and fluorometrie data from mammalian muscles. Correlations and an approach to a biochemical synthesis. Federation Proc. 41: 176–184.

    Google Scholar 

  • CHINET, A., CLAUSEN, T., and GIRARDIER, L. (1977): Microcalorimetric determination of energy expenditure due to active sodium-potassium transport in the soleus muscle and brown adipose tissue of the rat. J. Physiol. 265: 43–61.

    Google Scholar 

  • COULSON, R.L. (1976): Energetics of isovolumic contractions of the isolated rabbit heart. J. Physiol. London, 260: 45–53, 1976.

    Google Scholar 

  • CRANEFIELD, P.F., and GREENSPAN, K. (1960): The rate of oxygen uptake of quiescent cardiac muscle. J. Gen. Physiol. 44: 235–250.

    Article  Google Scholar 

  • CREESE, R. (1968): Sodium fluxes in diaphragm muscle and the effects of insulin and serum proteins. J. Physiol. 197: 255–278.

    Google Scholar 

  • DAWSON, M.J., GADIAN, D.G., and WILKIE, D.R. (1980): Mechanical relaxation rate and metabolism studied in fatiguing muscle by phosphorus nuclear magnetic resonance. J. Physiol. 299: 465–484.

    Google Scholar 

  • EISENBERG, E., and HILL, T.L. (1978): A crossbridge model of muscle contraction. Prog. Biophys. Mol. Biol. 33: 55–82.

    Article  Google Scholar 

  • ELZINGA, G., and WESTERHOF, N. (1980): Pump function of the feline left heart: changes with heart rate and its bearing on the energy balance. Cardiovasc. Res. 14: 81–92.

    Article  Google Scholar 

  • ELZINGA, G., and WESTERHOF, N. (1981): “Pressure volume” relations in isolated cat trabeculae. Circ. Res. 49: 388–394.

    Google Scholar 

  • FORD, L.E. (1980): Effect of afterload reduction on myocardial energetics. Circ. Res. 46: 161–166.

    Google Scholar 

  • GIBBS, C.L. (1969): The energy output of normal and anoxic cardiac muscle. In: Comparative Physiology of the Heart: Current Trends, pp. 78–92, McCann, F.V. (Ed.) Birkhauser Verlag, Basel.

    Google Scholar 

  • GIBBS, C.L. (1974): Cardiac Energetics. In: The Mammalian Myocardium, pp. 105–133. Langer, G.A. and Brady, A.J. (Eds.) Wiley, New York.

    Google Scholar 

  • GIBBS, C.L. (1978): Cardiac Energetics. Physiol. Rev. 58: 174–254.

    Google Scholar 

  • GIBBS, C.L. (1981): A re-examination of two determinants of cardiac energy expenditure. J. Molec. Cell. Cardiol. 13: 2.

    Article  Google Scholar 

  • GIBBS, C.L. and CHAPMAN, J.B. (1979a): Cardiac energetics. In: Handbook of Physiology. Cardiovascular System. Sect. 2, vol. 1, Chapt. 22, p. 775–804, Am. Physiol. Soc. Bethesda, M.D.

    Google Scholar 

  • GIBBS, C.L. and CHAPMAN, J.B. (1979b): Cardiac heat production. Annu.Rev.Physiol. 41: 507–519.

    Article  Google Scholar 

  • GIBBS, C.L. and GIBSON, W.R. (1970): Energy production in cardiac isotonic contractions. J.Gen.Physiol. 56: 732–750.

    Article  Google Scholar 

  • GIBBS, C.L. and LOISELLE, D.S. (1978): The energy output of tetaniz-ed cardiac muscle: species differences. Pfulgers Archiv. 373: 31–39.

    Article  Google Scholar 

  • GIBBS, C.L., MOMMAERTS, W.F.H.M. and RICCHIUTI, N.V. (1967): Energetics of cardiac contractions. J. Physiol. London, 191: 25–46.

    Google Scholar 

  • GODFRAIND DE-BECKER, A. (1972): Heat production and fluorescence changes of toad sartorius muscle during aerobic recovery after a short tetanus. J. Physiol. 223: 719–734.

    Google Scholar 

  • GRANDE, F. and TAYLOR, H.L. (1965): Adaptive changes in the heart, vessels, and patterns of control under chronically high loads. In: Handbook of Physiology. Circulation, Sect. 2, Vol. III, Chapter 74, 2615–2677. Am. Physiol. Soc. Bethesda.

    Google Scholar 

  • HASSELBACH, W. (1976): Release and uptake of calcium by the sarcoplasmic reticulum. In: Molecular Basis of Motility, p. 81–91. Herlmeyer, L., Ruegg, J.C. and Wieland, T. (Eds.). Springer-Verlag, New York.

    Google Scholar 

  • HAWORTH, R.A., HUNTER, D.R. and BERKOFF, H.A. (1981): Contracture in isolated adult rat heart cells. Role of Ca2+ ATP, and com-partmentation. Circ. Res. 49: 1119–1128.

    Google Scholar 

  • HEARSE, D.J. (1979): Oxygen deprivation and early myocardial contractile failure: a reassessment of the possible role of adenosine triphosphate. Am. J. Cardiol. 44: 1115–1121.

    Article  Google Scholar 

  • HIMMS-HAGEN, J. (1976): Cellular thermogenesis. Annu. Rev. Physiol. 38: 315–351.

    Article  Google Scholar 

  • HOMSHER, E. and KEAN, C.J. (1978): Skeletal muscle energetics and metabolism. Annu. Rev. Physiol. 40: 93–131.

    Article  Google Scholar 

  • HOMSHER, E. and KEAN, C.J. (1981): Unexplained enthalpy production in isometric contractions and its relation to intracellular calcium movements. In: The Regulation of Muscle Contraction: Excitation-Contraction Coupling. Grimwell, A.D. & Brazier, M.A.B. (Eds.), pp. 337–347, Academic Press, New York.

    Google Scholar 

  • HOOKE, N.F. (1982): Transient twich and summated tetanic behaviour of the Hill-Eisenberg model of muscle contraction. Proc. Aust. Physiol. Pharmacol. Soc. 13, (In press).

    Google Scholar 

  • HUXLEY, A.F. (1957): Muscle structure and theories of contraction. Prog. Biophys. Biophys. Chem. 7: 225–318.

    Google Scholar 

  • HUXLEY, A.F. and SIMMONS, R.M. (1971): Proposed mechanisms of force generation in striated muscle. Nature London, 233, 533–538.

    Article  Google Scholar 

  • JEWELL, B.R. (1977): A re-examination of the influence of muscle length on myocardial performance. Circulation, 40, 221–230.

    Google Scholar 

  • KAMMERMEIER, H., SCHMIDT, R. and JUNGLING, E. (1982): Free energy change of ATP hydrolysis: a causal factor of early hypoxic failure of the myocardium. J. Molec. Cell. Cardiol. (In press).

    Google Scholar 

  • KHALAFBEIGUE, F., SUGA, H. and SAGAWA, K. (1979): Left ventricular systolic pressure-volume area correlates with oxygen consumption. Am. J. Physiol. 237, H566–H569.

    Google Scholar 

  • KLEIBER, M. (1947): Body size and metabolic rate. Physiol. Rev. 27: 511–541.

    Google Scholar 

  • KREBS, H.A. (1950): Body size and tissue respiration. Biochimica et biophysica acta 4: 249–269.

    Article  Google Scholar 

  • LANGER, G.A. (1967): Sodium exchange in dog ventricular muscle. Relation to frequency of contraction and its possible role in the control of myocardial contractility. J. Gen. Physiol. 50: 1221–1239.

    Article  Google Scholar 

  • LANGER, G.A. (1968): Ion fluxes in cardiac excitation and contraction and their relation to myocardial contractility. Physiol. Rev. 48: 708–757.

    Google Scholar 

  • LEHNINGER, A.L. (1965): Bioenergetics. The Molecular Basis of Biological Energy Transformations, pp. 172–198, Benjamin, New York.

    Google Scholar 

  • LOCHNER, W., ARNOLD, G. and MULLER-RUCHHOLTZ, E.R. (1968): Metabolism of the artificially arrested heart and of the gas-perfused heart. Am. J. Cardiol. 22: 299–311.

    Article  Google Scholar 

  • LOISELLE, D.S. (1982): On the stretch-induced increase in resting metabolism of isolated papillary muscle. Biophys. J. (In press).

    Google Scholar 

  • LOISELLE, D.S. and GIBBS, C.L. (1979): Species differences in cardiac energetics. Am. J. Physiol. 237: H90–H98.

    Google Scholar 

  • LOISELLE, D.S., WENDT, I.R., and HOH, J.F.Y. (1982): Energetic consequences of thyroid-modulated shifts in isomyosin distribution in the rat. J. Muse. Res. Cell. Motil. (In press).

    Google Scholar 

  • MILLWARD, D.J., GARLICK, P.J., JAMES, W.P.T., SANDER, P. and WATERLOW, J.C. (1976): Protein turnover. In: Protein Metabolism and Nutrition: Proceedings. Cole, D.J.A., Boorman, K.N., Buttery, P.J., Lewis, D., Neale, R.J., & Swan, H. (Eds.). pp. 4969. Butterworths, London.

    Google Scholar 

  • MITCHELL, P. (1961): Coupling of phosphorylation to electron and hydrogen transfer by a chemi-osmotic type of mechanism. Nature 191: 144–148.

    Article  Google Scholar 

  • MONROE, R.G. and FRENCH, G.N. (1961): Left ventricular pressure-volume relationships and myocardial oxygen consumption in the isolated heart. Circ. Res. 9: 362–374.

    Google Scholar 

  • MCCALL, D. (1979): Cation exchange and glycoside binding in cultured rate heart cells. Am. J. Physiol. 236: C87–C95.

    Google Scholar 

  • PANERAI, R.B. (1980): A model of cardiac muscle mechanics and energetics. J. Biomechanics. 13: 929–940.

    Article  Google Scholar 

  • PENPARKGUL, S. and SCHEUER, J. (1969): Metabolic comparisons between hearts arrested by calcium deprivation or potassium excess Am. J. Physiol. 217: 1405–1412.

    Google Scholar 

  • ROBERTSON, S.P., JOHNSON, J.D. and POTTER, J.D. (1981): The time-course of Ca2+ exchange with calmodulin, troponin, paralbumin, and myosin in response to transient increases in Ca2+. Biophys. J. 34: 559–569.

    Article  Google Scholar 

  • SAGAWA, K. (1978): The ventricular pressure-volume diagram revisited. Circ. Res. 43: 667–687.

    Google Scholar 

  • SCHREIBER, S.S, EVANS, C.D., ORATZ, M. and ROTHSCHILD, M.A. (1981): Protein synthesis and degradation in cardiac stress. Circ. Res. 48: 601–611.

    Google Scholar 

  • SCRUTTON, M.C. and UTTER, M.F. (1968): The regulation of glycolysis and gluconeogenesis in animal tissues. Annu. Rev. Biochem. 37: 249–302.

    Article  Google Scholar 

  • SOLARO, R.M., WISE, R.M., SHINER, J.S. and BRIGGS, F.N. (1974): Calcium requirements for cardiac myofibrillar activation. Circulation Res. 34: 525–530.

    Google Scholar 

  • SUGA, H. (1979): External mechanical work from relaxing ventricle. Am. J. Physiol. 236: H494–H497.

    Google Scholar 

  • SUGA, H., HAYASHI, T. and SHIRAHATA, M. (1981): Ventricular systolic pressure volume area as predictor of cardiac oxygen consumption. Am. J. Physiol. 240: H39–H44.

    Google Scholar 

  • TEN VELDEN, G.H.M., ELZINGA, G. and WESTERHOF, N. (1982): Left ventricular energetics: heat loss and temperature distribution of canine myocardium. Circ. Res. 50: 63–73.

    Google Scholar 

  • WEBER, K.T., JANICKI, J.S. and HEFFNER, L.L. (1976): Left ventricular forcelength relations of isovolumic and ejecting contractions. Am. J. Physiol. 23: 337–343.

    Google Scholar 

  • WESTERHOF, N. and ELZINGA, G. (1978): The apparent source resistance of heart and muscle. Ann. Biomed. Eng. 6: 16–32.

    Article  Google Scholar 

  • WILKIE, D.R. (1960): Thermodynamics and the interpretation of biological heat measurements. Prog. Biophys. Biophys. Chem. 10: 260–298.

    Google Scholar 

  • WILKIE, D.R. (1974): The efficiency of muscular contraction. J. Mechanochem. Cell. Motil. 2: 257–267.

    Google Scholar 

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Author information

Authors and Affiliations

  1. Department of Physiology, Monash University, Melbourne, Australia

    C. L. Gibbs

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  1. C. L. Gibbs
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Editor information

Editors and Affiliations

  1. Sydney Hospital and Department of Medicine, University of Sydney, Sydney, Australia

    Leopold Dintenfass

  2. Freeman Hospital, University of Newcastle, Newcastle-upon-Tyne, England

    Desmond G. Julian

  3. The Oregon Health Sciences University, Portland, Oregon, USA

    Geoffrey V. F. Seaman

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© 1983 Plenum Press, New York

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Gibbs, C.L. (1983). Thermodynamics and Cardiac Energetics. In: Dintenfass, L., Julian, D.G., Seaman, G.V.F. (eds) Heart Perfusion, Energetics, and Ischemia. NATO Advanced Science Institutes Series, vol 62. Springer, Boston, MA. https://doi.org/10.1007/978-1-4757-0393-1_27

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  • DOI: https://doi.org/10.1007/978-1-4757-0393-1_27

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  • Online ISBN: 978-1-4757-0393-1

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