Abstract
Humans alter the rate of heat transfer from deep tissues to the body surface by actively adjusting the vasomotor state of internal organs where heat is produced and of the blood vessels of the skin where heat is lost to the environment. In cold environments heat loss is minimized by constriction of cutaneous arterioles and veins. The redistribution of blood flow and blood volume from superficial to deep vessels increases thermal insulation. When heat losses must be increased, the opposite responses are elicited. Then the cardiovascular system must provide for large increments in skin blood flow and also a substantial volume of blood must be mobilized to the cutaneous veins from the central vasculature. Thermal balance is modified further by shivering or sweating. This paper focuses on adjustments of the systemic and regional circulations that alter heat transfer during heat stress. Control of sweating is not discussed.
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References
ABRAMSON, D.I. (1967): “Circulation in the Extremities”, chapt. 11, pp. 229–259, Academic Press, New York.
AMBERSON, W.R. (1943): Physiologic adjustments to the standing posture. Bull. Maryland Univ. School Med. 27: 127–145.
BEISER, G.D., ZELIS, R., EPSTEIN, S.E., MASON, D.T., and BRAUNWALD, E. (1970): The role of skin and muscle resistance vessels in reflexes mediated by the baroreceptor system. J. Clin. Invest. 49: 255–231.
BERLYNE, G.M., FINBER, J.P.M., and YORAN, C. (1974): The effect of B-adrenergic blockade on body temperature and plasma renin activity in heat-exposed man. Brit. J. Clin. Pharmacol. 1: 307–312.
BEVEGARD, B.S., and SHEPHERD, J.T. (1966): Reaction in man of resistance and capacity vessels in forearm and hand to leg exercise. J. Appl. Physiol. 21: 123–132.
BEVEGARD, S., CASTENFORS, J., LINDBLAD, L.E, and TRANESJO, J. (1977): Blood pressure and heart rate regulating capacity of the carotid sinus during changes in blood volume distribution in man. Acta Physiol. Scand. 99: 300–312.
BLAIR, D.A, GLOVER, W.E, and RODDIE, I.C. (1961): Vasomotor responses in the human arm during leg exercise. Circulation Res. 9: 264–274.
BRENGELMANN, G.L. (1977): Control of sweating rate and skin blood flow during exercise, in “Problems with Temperature Regulation During Exercise”, E.R. Nadel (Ed.), pp. 27–48, Academic Press, New York.
BRENGELMANN, G.L. (1983): Circulatory adjustments to exercise and heat stress. Annu. Rev. Physiol. 44, in press.
BRENGELMANN, G.L., FREUND, P.R., ROWELL, L.B., OLERUD, J.E., and KRANING, K.K. (1981): Absence of active cutaneous vasodilation associated with congenital absence of sweat glands in man. Am. J. Physiol. 240: H571–H575.
BRENGELMANN, G.L., JOHNSON, J.M., HERMANSEN, L., and ROWELL, L.B. (1977): Altered control of skin blood flow during exercise at high internal temperature. J. Appl. Physiol.: Respirât. Environ. Exercise Physiol. 43: 790–794.
BROWN, A.C., and BRENGELMANN, G.L. (1970): The interaction of peripheral and central inputs in the temperature regulation system, In “Physiological and Behavioural Temperature Regulation”, J.D. Hardy, A.P. Gagge, and J.A.J. Stolwijk (Eds.). chapt. 47, pp. 648–702, Charles C. Thomas, Springfield, IL.
CHRISTENSEN, N.J. (1979): Plasma noradrenaline and adrenaline measured by isotope-derivative assay. Danis Med. Bull. 26: 17–56.
CLAUSEN, J.P. (1977): Effect of physical training on cardiovascular adjustments to exercise in man. Physiol. Rev. 57: 779–815.
CONRADT, M., KULLMAN, R., MATSUZAKI, T., and SIMON, E. (1975): Arterial baroreceptor function in differential cardiovascular adjustments induced by central thermal stimulation. Basic Res. Cardiol. 70: 10–28.
CROSSLEY, R.J., GREENFIELD, A.D.M., PLASSARAS, G.C., and STEPHENS, D. (1966): The interrelation of thermoregulatory and baroreceptor reflexes in the control of blood vessels in the human forearm. J. Physiol. London 183: 628–636.
DETRY, J.M.R., BRENGELMANN, G.L., ROWELL, L.B. and WYSS, C. (1972): Skin and muscle components of forearm blood flow in directly heated resting man. J. Appl. Physiol. 32: 506–511.
DOBA, N. and REIS, D.J. (1974). Role of the cerebellum and the vestibular appartus in regulation of orthostatic reflexes in the cat. Circulation Res. 34: 9–18.
EDHOLM, O.G., FOX, R.H., and MACPHERSON, R.K. (1957): Vasomotor control of the cutaneous blood vessels in the human forearm. J. Physiol. London 139: 455–465.
EISMAN, M.M., and ROWELL, L.B. (1977): Renal vascular response to heat stress in baboons — role of renin-angiotensin. J. Appl. Physiol.: Respirat. Environ. Exercise Physiol. 43: 739–746.
ESCOURROU, P., FREUND, P.R., ROWELL, L.B., and JOHNSON, D.G. (1982): Splanchnic vasoconstriction in heat-stressed man — role of the renin-angiotensin system. J. Appl. Physiol.: Respirat. Environ. Exercise Physiol., in press.
FOX, R.J., and EDHOLM, O.G. (1963): Nervous control of the cutaneous circulation. Brit. Med. Bull. 19: 110–114.
FREUND, P.R, BRENGELMANN, G.L., HALAR, E., and ROWELL, L.B. (1982): Elevated threshold and reduced slope of skin blood flow response in hyperthermic paraplegic man. Fed. Proc. 41: 4130.
GREENFIELD, A.D.M. (1963): The circulation through the skin. In “Handbook of Physiology. Circulation”, W.F. Hamilton and P. Dow (Eds.), sect. 2., vol. II, chapt. 39, pp. 1325–1351. American Physiological Society, Washington, D.C.
HALES, J.R.S. (1974): Physiological responses to heat, In “MTP International Review of Science, Physiology”, D. Robertshaw (Ed.), ser. 1, vol. 7, pp. 107–162, Butterworth, London.
HALES, J.R.S., ROWELL, L.B., and KING, R.B. (1979): Regional distribution of blood flow in awake heat-stressed baboons. Am. J. Physiol. 237: H705–H712.
HAYWARD, J.N., and BAKER, M.A. (1969): A comparative study of the role of the cerebral arterial blood in the regulation of brain temperature in five mammals. Brain Res. 16: 417–440.
HEISTAD, D.D, and ABBOUD, F.M. (1974): Factors that influence blood flow in skeletal muscle and skin. Anesthesiology 41: 139–156.
HENRY, J.P. (1951): The significance of the loss of blood volume into the limbs during pressure breating. Aviat. Med. 22: 31–38.
HENRY, J.P. and GAUER, O.H. (1950): The influence of temperature upon venous pressure in the foot. J. Clin. Invest. 29: 855–861.
JESSEN, C., and MAYER, E. Th, (1971): Spinal cord and hypothalamus as core sensors of temperature in the conscious dog. Pflugers Arch. 324: 189–204.
JESSEN, C., and SIMON, E. (1971): Spinal cord and hypothalamus as core sensors of temperature in the conscious dog. III. Identity of functions. Pflugers Arch. 324: 217–226, 1971.
JOHNSON, J.M. (1979): Responses of forearm blood flow to graded leg exercise in man. J. Appl. Physiol.: Respirat. Environ. Exercise Physiol. 46: 457–462.
JOHNSON, J.M., BRENGELMANN, G.L., and ROWELL, L.B. (1976): Interactions between local and reflex influences on human forearm skin blood flow. J. Appl. Physiol. 41: 826–831.
JOHNSON, J.M., NIEDERBERGER, M., ROWELL, L.B., EISMAN, M.M., and BRENGELMANN, G.L. (1973): Competition between cutaneous vasodilator and vasoconstrictor reflexes in man. J. Appl. Physiol. 35: 798–803.
JOHNSON, J.M., ROWELL, L.B., and BRENGELMANN, G.L. (1974a): Modification of the skin blood flow-body temperature relationship by upright exercise. J. Appl. Physiol. 37: 880–886.
JOHNSON, J.M., ROWELL, L.B., NIEDERBERGER, M., and EISMAN, M.M. (1974b): Human splanchnic and forearm vasoconstrictor responses to reduction of right atrial and aortic pressure. Circulation Res. 34: 515–524.
KIM, Y.D., LAKE, C.D., LEES, D.E., SCHUETTE, W.H., BULE, J.M., WEISE, V., and KOPIN, I.H. (1979): Hemodynamic and plasma catecholamine responses to hyperthermic cancer therapy in humans. Am. J. Phyisol. 237: H570–H574.
KROGH, A. (1912): The regulation of the supply of blood to the right heart. Scand. Arch. Physiol. 27: 227–248.
LEVY, B., GHAEM, A., VERPILLAT, J.M., and MARTINEAUD, J.P. (1975): Antagonistic effects upon cutaneous circulation of muscular exercise and exposure to a high ambient temperature. Pflugers Arch. 359: 137–146.
MILVY, P. (Ed.) (1977): “The Marathon: Physiological, Medical, Epidemiological, and Psychological Studies”, The New York Academy of Sciences, New York.
MOSLEY, J.G. (1969): A reduction in some vasodilator responses in freestanding man. Cardiovascular Res. 3: 14–21.
NADEL, E.R., CAFARELLI, E., ROBERTS, M.F., and WENGER, C.B. (1979): Circulatory regulation during exercise in different ambient temperatures. J. Appl. Physiol.: Respirât. Environ. Exercise Physiol. 46: 430–437.
NADEL, E.R., FORTNEY, S.M., and WENGER, C.B. (1980): Effect of hydration state on circulatory and thermal regulations. J. Appl. Physiol.: Respirât. Environ. Exercise Physiol. 49: 715–721.
NIELSEN, M., HERRINGTON, L.P., and WINSLOW, C.E.A. (1939): The effect of posture on peripheral circulation. Am. J. Physiol. 127: 573–580.
PROPPE, D.W., BRENGELMANN, G.L. and ROWELL, L.B. (1976): Control of baboon limb blood flow and heart rate: role of skin vs. core temperature. Am. J. Physiol. 231: 1457–1465.
RADIGAN, L.R., and ROBINSON, S. (1949): Effects of environmental heat stress and exercise on renal blood flow and filtration rate. J. Appl. Physiol. 2: 185–191.
RODDIE, I.C., and SHEPHERD, J.T. (1957): The effects of carotid artery compression in man with special reference to changes in vascular resistance in the limbs. J. Physiol. London 139: 377–384.
RODDIE, I.C., SHEPHERD, J.T., and WHELAN, R.F. (1958): Reflex changes in human skeletal muscle blood flow associated with intrathoracic pressure changes. Circulation Res. 6: 232–238.
ROWELL, L.B. (1974): Human cardiovascular adjustments to exercise and thermal stress. Physiol. Rev. 54: 75–159.
ROWELL, L.B. (1977): Reflex control of the cutaneous vasculature. J. Invest. Dermatol. 69: 154–166, 1977.
ROWELL, L.B. (1981): Active neurogenic vasodilation in man. In “Vasodilation”, P.M. Vanhoutte and I. Leusen (Eds.), pp. 1–17, Raven Press, New York.
ROWELL, L.B. (1982): Cardiovascular adjustments to thermal stress, in “Handbook of Physiology. Peripheral Circulation and Organ Blood Flow,” J.T. Shepherd and F.M. Abboud (Eds.), American Physiological Society, Bethesda, MD, in press.
ROWELL, L.B., BLACKMAN, J.R., MARTIN, R.H., MAZZARELLA, J.A., and BRUCE, R.A. (1965): Hepatic clearance of indocyanine green in man under thermal and exercise stresses. J. Appl. Physiol. 20: 384–394.
ROWELL, L.B., BRENGELMANN, G.L., BLACKMON, J.R., TWISS, R.D., and KUSUMI, F. (1968): Splanchnic blood flow and metabolism in heat stressed man. J. Appl. Physiol. 24: 475–484.
ROWELL, L.B., BRENGELMANN, G.L., DETRY, J.M.R., and WYSS, C. (1971a): Venomotor responses to rapid changes in skin temperature in exercising man. J. Appl. Physiol. 30: 64–71.
ROWELL, L.B., BRENGELMANN, G.L., DETRY, J.M.R., and WYSS, C. (1971b): Venomotor responses to local and remote thermal stimuli to skin in exercising man. J. Appl. Physiol. 30: 72–77.
ROWELL, L.B., DETRY, J.M.R., PROFANT, G.R, and WYSS, C. (1971c): Splanchnic vasoconstriction in hyperthermic man — role of falling blood pressure. J. Appl. Physiol. 31: 864–869.
ROWELL, L.B., FREUND, P.R., and BRENGELMANN, G.L. (1982): Cutaneous vascular response to exercise and acute hypoxia. J. Appl. Physiol.: Respirat. Environ. Exercise Physiol., in press.
ROWELL, L.B., MARX, H.J., BRUCE, R.A., CONN, R.D, and KUSMUI, F., (1966): Reductions in cardiac output, central blood volume, and stroke volume with thermal stress in normal men during exercise. J. Clin. Invest. 45: 1801–1816.
ROWELL, L.B., MURRAY, J.A., BRENGELMANN, G.L., and KRANING, K.K., II. (1969): Human cardiovascular adjustments to rapid changes in skin temperature in exercising man. Circulation Res. 24: 711–724.
ROWELL, L.B., WYSS, C.R., and BRENGELMANN, G.L. (1973): Sustained human skin and muscle vasoconstriction with reduced baroreceptor activity. J. Appl. Physiol. 34: 639–643, 1973.
SHEPHERD, J.T. (1963). “Physiology of the Circulation in Human Limbs in Health and Disease”, Saunders, Philadelphia.
SHEPHERD, J.T., and VANHOUTTE, P.M. (1975): “Veins and Their Control”, Saunders, Philadelphia.
SIMON, E., and RIEDEL, W. (1975): Diversity of regional sympathetic outflow in integrative cardiovascular control: patterns and mechanisms. Brain Res. 87: 323–333.
TAM, H.S., DARLING, R.C., CHEH, H.Y., and DOWNEY, J.A. (1978): The dead zone of thermoregulation in normal and paraplegic man. Can. J. Physiol. Pharmacol. 56: 976–983.
TYDEN, G. (1977): Aspects of cardiovascular reflex control in man. Acta Physiol. Scand., Suppl. 448: 1–62.
VANHOUTTE, P.M. (1980): Physical factors of regulation, in “Handbook of Physiology. The Cardiovascular System. Vascular Smooth Muscle”, D.F. Bohr, A.P. Somlyo, and H.V. Sparks, Jr. (Eds.), sect. 2., vol. II, chapt. 16, pp. 443–474, American Physiological Society, Bethesda, MD.
WENGER, C.B., ROBERTS, M.F., STOLWIJK, J.A.J., and NADEL, E.R. (1975): Forearm blood flow during body temperature transients produced by leg exercise. J. Appl. Physiol. 38: 58–63.
WENNERGREN, G. (1975): Aspects of central integrative and efferent mechanisms in cardiovascular reflex control. Acta Physiol. Scand., Suppl. 428: 5–53, 1975.
WYSS, C.R., BRENGELMANN, G.L., JOHNSON, J.M., ROWELL, L.B., and NIEDERBERGER, M. (1974): Control of skin blood flow, sweating and heart rate: role of skin vs. core temperature. J. Appl. Physiol. 36: 726–733.
WYSS, C.R., BRENGELMANN, G.L., JOHNSON, J.M., ROWELL, L.B., and SILVERSTEIN, D. (1975): Altered control of skin blood flow at high skin and core temperatures. J. Appl. Physiol. 38: 839–845.
ZITNIK, R.S., AMBROSIONI, E., and SHEPHERD, J.T. (1971): Effect of temperature on cutaneous venomotor reflexes in man. J. Appl. Physiol. 31: 507–512.
ZOLLER, R.P., MARK, A.L., ABBOUD, F.M., SCHMID, P.G., and HEISTAD, D.D. (1972): The role of low pressure baroreceptors in reflex vasoconstrictor responses in man. J. Clin. Invest. 51: 2967–2972.
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Rowell, L.B. (1983). The Cardiovascular System and Heat Transfer. In: Dintenfass, L., Julian, D.G., Seaman, G.V.F. (eds) Heart Perfusion, Energetics, and Ischemia. NATO Advanced Science Institutes Series, vol 62. Springer, Boston, MA. https://doi.org/10.1007/978-1-4757-0393-1_25
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