Abstract
In the last decade it has become clear, that a number of immunological diseases are related to imbalances of purine metabolism in lymphocyte subpopulations(1,2,3). Information regarding the enzymatic make-up and metabolic characteristics of lymphocyte subpopulations, both in healthy individuals and in patients, might contribute to a better diagnosis of immunological diseases and be of importance for the development of immuno-regulatory drugs. Not only T and B cell sub-populations, but also T and B cell subsets should be included in such studies.
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van Laarhoven, J.P.R.M., Spierenburg, G.T., Collet, H., Delespesse, G., De Bruyn, C.H.M.M. (1984). Purine Interconversion Pathways in T, B, Tγ and T-Tγ Cells from Human Peripheral Blood. In: De Bruyn, C.H.M.M., Simmonds, H.A., Müller, M.M. (eds) Purine Metabolism in Man-IV. Advances in Experimental Medicine and Biology, vol 165. Springer, Boston, MA. https://doi.org/10.1007/978-1-4757-0390-0_23
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DOI: https://doi.org/10.1007/978-1-4757-0390-0_23
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