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Dopamine Receptor Agonists pp 317–332Cite as

Dopaminergic Mechanisms in the Control of Aldosterone Secretion

A Critical Appraisal

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Part of the book series: New Horizons in Therapeutics ((NHTH))

Abstract

Dopamine, a precursor of the sympathetic neurotransmitter norepinephrine, is itself a neurotransmitter in the central nervous system (Hornykiewicz, 1966). Dopamine also may serve as a neurotransmitter in the periphery, as it inhibits prolactin secretion directly at the pituitary lactotroph and dilates the renal and mesenteric vascular beds (MacLeod, 1976; Goldberg, 1975).

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References

  • Ackerman, D. M., Weinstock, J., Wiebelhans, V. D., and Berkowitz, B., 1982, Renal vasodilators and hypertension, Drug Dev. Res. 2:283–297.

    Article  CAS  Google Scholar 

  • Aguilera, G., and Catt, K.J., 1984, Regulation of aldosterone secretion during altered sodium intake, J. Steroid Biochem. (in press).

    Google Scholar 

  • Alexander, R. W., Gill, J. R., Jr., Yamabe, H., Lovenberg, W., and Kaiser, H. R., 1974, Effects of dietary sodium and of acute saline infusion on the interrelationship between dopamine excretion and adrenergic activity in man, J. Clin. Invest. 54:194–200.

    Article  PubMed  CAS  Google Scholar 

  • Aona, T., Shioji, T., Kinugasa, T., Onishi, T., and Kurachi, K., 1978, Clinical and endocrinological analysis of patients with galactorrhea and menstrual disorders due to sulpiride and metoclopramide, J. Clin. Endocrinol. Metab. 47:675–680.

    Article  Google Scholar 

  • Bauman, G., and Loriaux, D. L., 1976, Failure of endogenous prolactin to alter renal salt and water excretion and adrenal function in man, J. Clin. Endocrinol. Metab. 43:643–649.

    Article  Google Scholar 

  • Besser, G. M., Parke, L., Edwards, C. R. W., Forsyth, I. A., and McNeilly, A. S., 1972, Galactorrhea: Successful treatment with reduction of plasma prolactin levels by bromergocryptine, Br. Med. J. 3:669–672.

    Article  PubMed  CAS  Google Scholar 

  • Birkhauser, M., Riondel, A., and Vallotton, M. B., 1979, Bromocriptine-induced modulation of the plasma aldosterone response to acute stimulation, Acta Endocrinol. (Kbh.) 91:294–30

    CAS  Google Scholar 

  • Brotzu, G., 1970, Inhibition by chlorpromazine of the effects of dopamine on the dog kidney, J. Pharm. Pharmacol. 22:664–667.

    Article  PubMed  CAS  Google Scholar 

  • Brown, R. D., Wisgerhof, M., Jiang, N. S., Kao, P., and Hagstad, R., 1981, Effect of metoclopramide on the secretion and metabolism of aldosterone in man, J. Clin. Endocrinol. Metab. 52:1014–1018.

    Article  PubMed  CAS  Google Scholar 

  • Brown, R. D., Billman, G. E., Kern, D. C, Stone, H. L., Jiang, N., Kao, P., and Hegstad, R., 1982, The effect of metoclopramide and dopamine on plasma aldosterone concentration in normal man and rhesus monkeys: A new model to study dopamine control of aldosterone secretion, J. Clin. Endocrinol. Metab. 55:828–832.

    Article  PubMed  CAS  Google Scholar 

  • Campbell, D. J., Mendelsohn, F. A. 0., Adam, W. R., and Funder, J. W., 1981, Is aldosterone secretion under dopaminergic control? Circ. Res. 49:1217–1227.

    Article  PubMed  CAS  Google Scholar 

  • Carey, R. M., 1982, Acute dopaminergic inhibition of aldosterone secretion in man is independent of angiotensin II and adrenocorticotropin, J. Clin. Endocrinol. Metab. 54:463–469.

    Article  PubMed  CAS  Google Scholar 

  • Carey, R. M., and Van Loon, G. R., 1982, Bromocriptine does not inhibit the aldosterone response to sodium depletion, J. Clin. Endocrinol. Metab. 55:162–165.

    Article  PubMed  CAS  Google Scholar 

  • Carey, R. M., Johanson, A. J., and Sief, S. M., 1977, The effects of ovine prolactin on water and electrolyte excretion in man are attributable to vasopressin contamination, J. Clin. Endocrinol. Metab. 44:850–858.

    Article  PubMed  CAS  Google Scholar 

  • Carey, R. M., Thorner, M. O., and Ortt, E. M., 1979, Effects of metoclopramide and bromocriptine on the renin-angiotensin-aldosterone system in man: Dopaminergic control of aldosterone, J. Clin. Invest. 63:727–735.

    Article  PubMed  CAS  Google Scholar 

  • Carey, R. M., Thorner, M. 0., and Ortt, E. M., 1980, Dopaminergic inhibition of metoclopramide-induced aldosterone secretion in man: Dissociation of responses to dopamine and bromocriptine, J. Clin. Invest. 66:10–18.

    Article  PubMed  CAS  Google Scholar 

  • Carey, R. M., Van Loon, G. R., Baines, A. D., and Ortt, E. M., 1981, Decreased plasma and urinary dopamine during dietary sodium depletion in man, J. Clin. Endocrinol. Metab. 52:903–909.

    Article  PubMed  CAS  Google Scholar 

  • Carey, R. M., Van Loon, G. R., Baines, A. D., and Kaiser, D. L., 1983, Suppression of basal and stimulated noradrenergic activity by the dopamine agonist, bromocriptine, in man, J. Clin. Endocrinol. Metab. 56(3):595–602.

    Article  PubMed  CAS  Google Scholar 

  • Carey, R. M., Townsend, L. M., Rose, C. E., Jr., Kaiser, D. L., and Ragsdale, N. V., 1984, The specific dopamine agonist, SKF 82526-J, increases renal blood flow and lowers blood pressure in essential hypertension, Hypertension (in press).

    Google Scholar 

  • Carlson, H. E., Briggs, J. E., and McCallum, R. W., 1977, Stimulation of prolactin secretion by metoclopramide in the rat, Proc. Soc. Exp. Biol. Med. 154:475–478.

    PubMed  CAS  Google Scholar 

  • Caron, M. G., Beaulieu, M., Raymond, V., Gagne, B., Drouin, J., Lefkowitz, R. J., and Labrie, F., 1978, Dopaminergic receptors in the anterior pituitary gland. Correlation of (3H)dihydroergocryptine binding with the dopaminergic control of prolactin release, J. Biol. Chem. 253:2244–2253.

    PubMed  CAS  Google Scholar 

  • Carroll, J. E., Campanile, C. P., and Goodfriend, T. L., 1980, Role of prolactin in aldosterone secretion, Clin. Res. 28:772A.

    Google Scholar 

  • Clarke, B. J., Scholtysik, G., and Fluckiger, E., 1978, Cardiovascular actions of bromocriptine, Acta Endocrinol. (Kbh.) 216(Suppl. 88):75–81.

    Google Scholar 

  • Carrodi, H., Fuxe, K., Hokfelt, T., Lidbrink, P., and Ungerstedt, U., 1973, Effect of ergot drugs on central catecholamine neurons. Evidence for stimulation of central dopamine neurons, J. Pharm. Pharmacol. 25:409–411.

    Article  Google Scholar 

  • Costa, G., Frisina, N., and DePasquale, R., 1980, Increased aldosterone secretion by sulpiride, Clin. Endocrinol. (Oxf.) 13:1–7.

    Article  CAS  Google Scholar 

  • Day, M. D., and Blower, P. R., 1975, Cardiovascular dopamine receptor Stimulation antagonized by metoclopramide, J. Pharm. Pharmacol. 27:276–278.

    Article  PubMed  CAS  Google Scholar 

  • del Pozo, E., Darragh, A., Lancranjan, I., Ebling, D., Burmeister, P., Buhler, F., Marbach, P., and Braun, P., 1977, Effect of bromocriptine on the endocrine system and fetal development, Clin. Endocrinol. (Suppl.) 6:47s–55s.

    Article  Google Scholar 

  • Delitala, G., Masala, A., Alagna, S., and Devilla, L., 1975, Metoclopramide and prolactin secretion in man: Effects of pretreatment with L-DOPA and 2-brom-alpha-ergocriptine (CB-154), IRCS, Med. Sei. Libr. Compend. 3:274.

    CAS  Google Scholar 

  • DiChiara, G., Vargiu, L., Porceddu, M. L., and Gessa, G. L., 1977, Bromocriptine: A rather specific stimulant of dopamine receptors regulating dopamine metabolism, Adv. Biochem. Psychopharmacol. 16:443–446.

    CAS  Google Scholar 

  • Dolphin, A., Jenner, P., Marsden, C. D., Pycock, C, and Tarsy, D., 1975, Pharmacological evidence for cerebral dopamine receptor blockade by metoclopramide in rodents, Psychopharmacologia 41:133–138.

    Article  PubMed  CAS  Google Scholar 

  • Drake, C. R.f, Ragsdale, N. V., Kaiser, D. L., and Carey, R. M., 1984, Dopamine inhibits aldosterone responses TO angiotensin II during sodium depletion in man, Metabolism (in press).

    Google Scholar 

  • Dunn, M. G., and Bosmann, H. B., 1981, Peripheral dopamine receptor identification: Properties of a specific dopamine receptor in the rat adrenal zona glomerulosa, Biochem. Biophys. Res. Commun. 99:1081–1087.

    Article  PubMed  CAS  Google Scholar 

  • Edwards, C. R. W., Al-Dujaili, E. A. S., Boscaro, M., Zuyyumi, S., Miall, P. A., and Rees, L. H., 1980, In vivo and in vitro studies on the effect of metoclopramide on aldosterone secretion, Clin. Endocrinol. (Oxf.) 13:45–50.

    Article  CAS  Google Scholar 

  • Fluckiger, E., and Wagner, H. R., 1968, 2-Br-alpha-Ergocriptine. Beeinflussung von Fertilitat and Lactation bei der Ratte, Experientia 24:1130.

    Article  PubMed  CAS  Google Scholar 

  • Fluckiger, E., Marko, M., Doepfner, W., and Niederer, W., 1976, Effects of ergot alkaloids on the hypothalamopituitary axis, Postgrad. Med. J. 52(Suppl. I):57–61.

    Article  PubMed  Google Scholar 

  • Fozard, J. R., and Mobarok Aki, A. T. M., 1978, Blockade of neuronal tryptamine receptors by metoclopramide, Eur. J. Pharmacol. 49:109–112.

    Article  PubMed  CAS  Google Scholar 

  • Fuxe, K., Carrodi, H., Hokfelt, T., Lidbrink, P., and Ungerstedt, U., 1974, Ergocornine and 2-Br-alpha-ergocriptine. Evidence for prolonged dopamine receptor stimulation, Med. Biol. 52:121–132.

    PubMed  CAS  Google Scholar 

  • Goldberg, L. I., 1972, Cardiovascular and renal actions of dopamine: Potential clinical applications, Pharmacol. Rev. 24:1–29.

    PubMed  CAS  Google Scholar 

  • Goldberg, L. I., 1975, The dopamine vascular receptor, Biochem. Pharmacol. 24:651–653.

    Article  PubMed  CAS  Google Scholar 

  • Goldberg, L. I., 1978, Characteristics of the vascular dopamine receptor: Comparison with other receptors, Fed. Proc. 37:2396–2402.

    PubMed  CAS  Google Scholar 

  • Goldberg, L. I., and Weder, A. B., 1980, Connections between endogenous dopamine, dopamine receptors and sodium excretion: Evidence and hypotheses, in: Recent Advances in Clinical Pharmacology (P. Turner and D. Shand, eds.), Churchill Livingstone, Edinburgh, pp. 149–166.

    Google Scholar 

  • Gordon, M. B., Moore, T. J., Dluhy, R. G., and Williams, G. H., 1983, Dopaminergic modulation of aldosterone responsiveness to angiotensin II with changes in sodium intake, J. Clin. Endocrinol. Metab. 56:340–345.

    Article  PubMed  CAS  Google Scholar 

  • Haning, R., Tait, S. A. S., and Tait, J. F., 1970, In vitro effects of ACTH, angiotensins, serotonin and potassium on Steroid output and conversion of corticosterone to aldosterone by isolated adrenal cells, Endocrinology 87:1146–1167.

    Article  Google Scholar 

  • Hay, A. M., 1975, The mechanism of action of metoclopramide, Gut 16:403.

    PubMed  CAS  Google Scholar 

  • Healy, D. L., and Burger, H. G., 1978, Sustained elevation of serum prolactin by metoclopramide: A clinical model of idiopathic hyperprolactinemia, J. Clin. Endocrinol. Metab. 46:709–714.

    Article  PubMed  CAS  Google Scholar 

  • Hertting, G., Reimann, W., Zumstein, A., Jackisch, R., and Starke, K., 1979, Dopaminergic feedback regulation of dopamine release in slices of caudate nucleus of the rabbit, Adv. Biosci. 18:145–150. ai]Hornykiewicz, O., 1966, Dopamine (3-hydroxytyramine) and brain function, Pharmacol. Rev. 18:925–964.

    CAS  Google Scholar 

  • Innes, I. R., and Nickerson, M., 1975, Norepinephrine, epinephrine, and the sympathomimetic amines. In: The Pharmacological Basis of Therapeutics (L. S. Goodman and A. Gilman, eds.), pp. 477–513, Macmillan, New York.

    Google Scholar 

  • Jenner, P., and Marsden, C. D., 1979, The substituted benzamides—a novel class of dopamine antagonists, Life Sci. 25:479–486.

    Article  PubMed  CAS  Google Scholar 

  • Jenner, P., Marsden, C. D., and Perringer, E., 1975, Behavioral and biochemical evidence for cerebral dopamine receptor blockade by metoclopramide in rodents, Br. J. Pharmacol. 54:275P–276P.

    PubMed  CAS  Google Scholar 

  • Jenner, P., Elliott, N. C, Clow, A., Reavill, C., and Marsden, C. D., 1978, A comparison of in vitro and in vivo dopamine receptor antagonism produced by substituted benzamide drugs, J. Pharm. Pharmacol. 30:46–48.

    Article  PubMed  CAS  Google Scholar 

  • Judy, W. V., Watanabe, A. M., Henry, D., Besch, H. R., and Aprison, B., 1978, Effect of L-dopa on sympathetic nerve activity and blood pressure in the spontaneously hypertensive rat, Circ. Res. 43:24–28.

    Article  PubMed  CAS  Google Scholar 

  • Kebabian, J. W., and Calne, D. B., 1979, Multiple receptors for dopamine, Nature 277:93–96.

    Article  PubMed  CAS  Google Scholar 

  • Kvetnansky, R., Weise, V. K., Thoa, N. B., and Kopin, I. J., 1979, Effects of chronic guanethidine treatment and adrenal medullectomy on plasma levels of catecholamines and corticosterone in forcibly immobilized rats, J. Pharmacol. Exp. Ther. 209:287–291.

    PubMed  CAS  Google Scholar 

  • Lew, J. Y., Hata, F., Ohashi, T., and Goldstein, M., 1977, The interactions of bromocriptine and lergotrile with dopamine and β-adrenergic receptors, J. Neural Transm. 41:109–121.

    Article  PubMed  CAS  Google Scholar 

  • Lichtenstein, L. S., Colwell, J. A., and Levine, J. H., 1976, Prolactin stimulates aldosterone biosynthesis, in: Program and Abstracts of the Sixth International Congress of Endocrinology, Union Offset Co., Canberra, Australia, p. 86.

    Google Scholar 

  • Lorenzi, M., Karam, J. H., Tsalikian, E., Bohannon, N. V., Gerich, J. E., and Forsham, P., 1979, Dopamine during alpha-and beta-blockade in man, J. Clin. Invest. 63:310–317.

    Article  PubMed  CAS  Google Scholar 

  • MacLeod, R. M., 1976, Regulation of prolactin secretion, in: Frontiers in Neuroendocrinology (L. Martini and W. F. Ganong, eds.), Raven Press, New York, pp. 169–194.

    Google Scholar 

  • Mantero, F., Boscaro, M., Opocher, G., Aramini, D., and Edwards, C. R. W., 1980, In vitro and in vivo effect of metergoline on aldosterone secretion, in: Program and Abstracts of the Sixth International Congress of Endocrinology, Union Offset Co., Canberra, Australia, p. 405.

    Google Scholar 

  • McCaa, R. E., Young, D. B., and Guyton, A. C, 1974, Evidence of a role of an unidentified pituitary factor regulating aldosterone secretion during altered sodium balance, Circ. Res. (Suppl.1):34–35.

    Google Scholar 

  • McCallum, R. W., Sowers, J. R., Hershman, J. M., and Sturdevant, R. A. L., 1976, Metoclopramide stimulates prolactin secretion in man, J. Clin. Endocrinol. Metab. 42:1148–1152.

    Article  PubMed  CAS  Google Scholar 

  • McKenna, T. J., Island, D. P., Nicholson, W. E., and Liddle, G. W., 1979, Dopamine inhibits angiotensin-stimulated aldosterone biosynthesis in bovine adrenal cells, J. Clin. Invest. 64:287–291.

    Article  PubMed  CAS  Google Scholar 

  • McKenna, T. J., Island, D. P., Nicholson, W. E., and Liddle, G. W., 1980, Stimulation of aldosterone prolactin by catecholamines in vitro, in: Program and Abstracts, Sixth International Congress of Endocrinology, Melbourne, Union Offset Co., Canberra, Australia, p. 407.

    Google Scholar 

  • Mori, M., Kobayashi, I., Ohshima, K., Maruta, S., Shomomura, Y., and Fukuda, H., 1980, Potentiation of sulpiride-induced prolactin secretion by sodium deprivation in man, Acta Endocrinol. (Kbh.) 94:25–29.

    CAS  Google Scholar 

  • Niemegeers, C. J. E., and Janssen, P. A. J., 1979, A systematic study of the pharmacological activities of the dopamine antagonists, Life Sci. 24:2201–2216.

    Article  PubMed  CAS  Google Scholar 

  • Norbiato, G., Bevilacqua, M., Raggi, U., Micossi, P., and Moroni, C, 1977, Metoclopramide increases plasma aldosterone in man, J. Clin. Endocrinol. Metab. 45:1313–1316.

    Article  PubMed  CAS  Google Scholar 

  • Norbiato, G., Bevilacqua, M., Vago, T., Reggi, U., and Malacco, E., 1982, Characterization of dopaminergic receptors by [H3]-ADTN binding in calf adrenal glomerulosa cells, in: Endocrinology of Hypertension (F. Mantero, E. G. Biglieri, and C. R. W. Edwards, eds.), Proceedings of the Serono Symposia, Vol. 50, Academic Press, London, pp. 133–141.

    Google Scholar 

  • Noth, R. H., McCallum, W., Contino, C, and Havelick, J., 1980, Tonic dopaminergic suppression of plasma aldosterone, J. Clin. Endocrinol. Metab. 51:64–69.

    Article  PubMed  CAS  Google Scholar 

  • Ogihara, T. S., Matsumara, S., Onishi, T., Miyai, K., Uozumi, T., and Kumahara, Y., 1977, Effect of metoclopramide-induced prolactin on aldosterone secretion in normal subjects, Life Sci. 20:523–526.

    Article  PubMed  CAS  Google Scholar 

  • Peringer, E., Jenner, P., Donaldson, I. M., and Marsden, C. D., 1976, Metoclopramide and dopamine receptor blockade, Neuropharmacology 15:463–469.

    Article  CAS  Google Scholar 

  • Pinder, R. M., Brogden, R. M., Sawyer, P. R., Speight, T. M., and Avery, F. S., 1976, Metoclopramide: A review of its pharmacological properties and clinical use, Drugs 12:81–131.

    Article  PubMed  CAS  Google Scholar 

  • Pratt, J. H., Ganguly, A., and Weinberger, M. H., 1979, Metoclopramide-induced aldosterone stimulation: Independence from pituitary and renal factors, Clin. Res. 27:680A.

    Google Scholar 

  • Semple, P. F., and Mason, P. A., 1978, Bromocriptine: Lack of effect on the angiotensin II and aldosterone responses to sodium deprivation, Clin. Endocrinol. 9:155–161.

    Article  CAS  Google Scholar 

  • Solyom, J., 1974, Anterior pituitary and aldosterone secretion, Lancet 2:507.

    Article  Google Scholar 

  • Sowers, J. R., and Stern, N., 1982, Influence of sodium homeostasis and circadean rhythm on dopaminergic modulation of 18-hydroxycorticosterone secretion in man, J. Clin. Endocrinol. Metab. 55:1046–1051.

    Article  PubMed  CAS  Google Scholar 

  • Sowers, J. R., McCallum, R. W., Hershman, J. M., Carlson, H. E., Sturdevant, R. A. L., and Meyer, N., 1976, Comparison of metoclopramide with other dynamic tests of prolactin secretion, J. Clin. Endocrinol. Metab. 43:679–681.

    Article  PubMed  CAS  Google Scholar 

  • Sowers, J. R., Carlson, H. E.. Brautbar, N., and Hershman, J. M., 1977, Effects of dexamethasone on prolactin and TSH responses to TRH and metoclopramide in man, J. Clin. Endocrinol. Metab. 44:327–341.

    Article  Google Scholar 

  • Sowers, J. R., Sollars, E., Barrett, J. D., and Sambhi, M. P., 1980a, Effect of L-DOPA and bilateral nephrectomy on the aldosterone response to metoclopramide, Life Sci. 27:497–501.

    Article  CAS  Google Scholar 

  • Sowers, J. R., Sollars, E., Tuck, M. L., and Asp, N., 1980b, Dopaminergic modulation of renin activity, aldosterone and prolactin secretion in the spontaneously hypertensive rat, Proc. Soc. Exp. Biol. Med. 164:598–601.

    CAS  Google Scholar 

  • Sowers, J. R., Tuck, M. L., Golub, M. S., and Sollars, E. G., 1980c, Dopaminergic control of aldosterone secretion is independent of alterations in renin secretion, Endocrinology 107:937–941.

    Article  CAS  Google Scholar 

  • Sowers, J. R., Brickman, A. S., Sowers, D. K., and Berg, G., 1981a, Dopaminergic modulation of aldosterone secretion in man is unaffected by glucocortieoids and angiotensin blockade, J. Clin. Endocrinol. Metab. 52:1078–1084.

    Article  CAS  Google Scholar 

  • Sowers, J. R., Sharp, B., Levin, E. R., Golub, M. S., Eggena, P., 1981b, Metoclopramide, a dopamine antagonist, stimulates aldosterone secretion in rhesus monkeys, but not in dogs or rabbits, Life Sci. 29:2171.

    Article  CAS  Google Scholar 

  • Sowers, J. R., Sharp, B., and McCallum, R. W., 1982a, Effect of domperidone, an extracerebral inhibitor of dopamine receptors, on thyrotropin, prolactin, renin, aldosterone and 18-hydroxycorticosterone secretion in man, J. Clin. Endocrinol. Metab. 54:869–871.

    Article  CAS  Google Scholar 

  • Sowers, J. R., Berg, G., Martin, V. S., and Mayes, D. M., 1982b, Dopaminergic modulation of aldosterone secretion in the rhesus monkey, Endocrinology 54:523.

    CAS  Google Scholar 

  • Szalay, K. S., 1973, In vitro aldosterone production: Effect of ethacrynic acid, chlorpromazine and veratrine, Acta Physiol. Acad. Sei. Hung. 43:275–279.

    CAS  Google Scholar 

  • Uberti, E. C, Fabbri, B. L., Margutti, A. R., Fersini, C. M., and Pansini, R., 1979, Effect of bromocriptine on the control of plasma aldosterone diurnal variation in normal supine man, Horm. Res. 10:64–78. ai]Valenzuela, J. E., 1976, Dopamine as a possible neurotransmitter in gastric relaxation, Gastroenterology 71:1019–1022.

    Article  PubMed  Google Scholar 

  • VanLoon, G. R., Sole, M. J., Bain, J., and Ruse, J. L., 1979, Effects of bromocriptine on plasma catecholamines in normal men, Neuroendocrinology 28:425–434.

    Article  CAS  Google Scholar 

  • Williams, F. A., Jr., Ragsdale, N. V., Kaiser, D. L., and Carey, R. M., 1984, Suppression of basal aldosterone secretion by L-DOPA in sodium deplete man, J. Clin. Endocrinol. Metab. (in press).

    Google Scholar 

  • Wilson, T. A., Kaiser, D. L., Peach, M. J., and Carey, R. M., 1983a, Possible mechanism of action of metoclopramide-induced aldosterone secretion: In vivo and in vitro studies in the sheep, Endocrinology 113:887–892.

    Article  CAS  Google Scholar 

  • Wilson, T. A., Kaiser, D. L., and Carey, R. M., 1983b, Dopaminergic inhibition of aldosterone secretion in man is independent of the autonomic nervous system, J. Clin. Endocrinol. Metab. 57:200–203.

    Article  CAS  Google Scholar 

  • Yeo, T., Thorner, M. O., Jones, A., Lowry, P. J., and Besser, G. M., 1978, Release from continuous perfused columns of isolated rat pituitary cells, Clin. Endocrinol. 10:123–130.

    Article  Google Scholar 

  • Yeo, T., Thorner, M. O., Jones, A., Lowry, P. J., and Besser, G. M., 1979, The effects of dopamine, bromocriptine, lergotrile and metoclopramide on prolactin release from continuous perfused columns of isolated rat pituitary cells, Clin. Endocrinol. 10:123–130.

    Article  CAS  Google Scholar 

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  1. Division of Endocrinology and Metabolism, Department of Internal Medicine, University of Virginia Medical Center, Charlottesville, Virginia, 22908, USA

    Robert M. Carey

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  1. Smith Kline & French Laboratories, Philadelphia, Pennsylvania, USA

    George Poste  & Stanley T. Crooke  & 

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Carey, R.M. (1984). Dopaminergic Mechanisms in the Control of Aldosterone Secretion. In: Poste, G., Crooke, S.T. (eds) Dopamine Receptor Agonists. New Horizons in Therapeutics. Springer, Boston, MA. https://doi.org/10.1007/978-1-4757-0310-8_15

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