Abstract
In-vitro test systems, most often based on mammalian cells, are today more and more being used to supplement or even replace in-vivo test systems. There has been an increasing interest in establishing cell lines and the availability of these has stimulated studies which were previously not possible. Investigators are today often seeking cultured lines with predefined characteristics. In most cases though, the presently available lines do not have normal tissue or cell counterparts and this can make correlation to normal controls more difficult. The collection of cell lines is all in all meeting difficulties today, due to the increasing rights of propriety and the fact that cell lines are now being patented.
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© 1991 Plenum Press, New York
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Fogh, J. (1991). Criteria for Evaluating and Choosing a Relevant Cell Line. In: Wilson, G., Davis, S.S., Illum, L., Zweibaum, A. (eds) Pharmaceutical Applications of Cell and Tissue Culture to Drug Transport. NATO ASI Series, vol 218. Springer, Boston, MA. https://doi.org/10.1007/978-1-4757-0286-6_4
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DOI: https://doi.org/10.1007/978-1-4757-0286-6_4
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