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Part of the book series: NATO ASI Series ((NSSA,volume 218))

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Abstract

This chapter is based on a panel discussion held at the end of the meeting to debate a number of key issues that had been raised in individual presentations.

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References

  1. Doluisio, J.T., Billups, N.F., Dittert, L.W., Sugita, E.T., Swintosky, J.V., J. Pharm. Sci. 1969, 58, 1196–1200.

    Article  PubMed  CAS  Google Scholar 

  2. Crone, C., 1963, The permeability of capillaries in various organs as determined by the use of the indicator dilution method. Acta Physiol. Scand. 58: 292–305.

    Article  PubMed  CAS  Google Scholar 

  3. Fenstermacher, J.D., Blasberg, R.G., and Patlak, C.S., 1981, Methods for quantifying the transport of drugs across the blood-brain systems. Pharmac. Ther. 14: 217–248.

    Article  CAS  Google Scholar 

  4. Oldendorf, W.H., 1974, Blood-brain barrier permeability to drugs. Ann. Rev. Pharmacol. 14: 239–248.

    Article  CAS  Google Scholar 

  5. Martin, Y.C., 1981, A practitioner’s perspective of the role of quantitative structure-activity analysis in medicinal chemistry, J. Med. Chem. 24, 229–237.

    Article  PubMed  CAS  Google Scholar 

  6. Taylor, D.C., Pownall, R., and Burke, W.J., 1985, The absorption of β-adreno receptors antagonist in the rat in situ small intestine; the effect of lipophilicity, J. Pharm. Pharmacol. 37, 280–283.

    Article  PubMed  CAS  Google Scholar 

  7. Rapoport, S.I., Ohno, K. and Pettigrew, K.D., 1979, Drug entry into the brain, Brain Res. 172: 354–359.

    Article  PubMed  CAS  Google Scholar 

  8. Levin, V.A., 1989, Relationship of octanol/water partition coefficient and molecular weight of rat brain capillary permeability. J. Med. Chem. 23: 682–684.

    Article  Google Scholar 

  9. Taylor, D.C., Lynch, J. and Leahy, D.E., 1990, Models for intestinal permeability to drugs, In Drug Delivery to the Gastrointestinal Tract (J.G. Hardy, S.S. Davis and CG. Wilson, eds), pp. 133–145, Ellis Horwood Ltd., Chichester, U.K.

    Google Scholar 

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© 1991 Plenum Press, New York

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Wilson, G., Davis, S.S., Illum, L., Zweibaum, A. (1991). Key Issues in the Use of Cell and Tissue Culture Systems. In: Wilson, G., Davis, S.S., Illum, L., Zweibaum, A. (eds) Pharmaceutical Applications of Cell and Tissue Culture to Drug Transport. NATO ASI Series, vol 218. Springer, Boston, MA. https://doi.org/10.1007/978-1-4757-0286-6_32

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  • DOI: https://doi.org/10.1007/978-1-4757-0286-6_32

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4757-0288-0

  • Online ISBN: 978-1-4757-0286-6

  • eBook Packages: Springer Book Archive

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