Role of Local [Ca+2] in the Control of Cell Function
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Ca+2 is believed to play an essential role in the regulation of cell function. While this has been suspected for many years, the inability to directly measure [Ca+2] in small cells of physiological interest precluded obtaining definitive insights into many aspects of this process. We have been interested in the mechanisms underlying the generation and regulation of force in smooth muscle and thus for many years, have been interested in the role of Ca+2 in this process.
KeywordsSmooth Muscle Cell Sarcoplasmic Reticulum Contractile Response Calcium Transient Calcium Chelator
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