Abstract
In general, peripheral T cells recognize foreign antigens only in the context of self MHC antigens. This MHC restriction has been shown, at least in some cases, to be determined by radio resistant elements within the thymus (Zinkernagel, 1978). Under some experimental protocols, however, developing T cells acquire instead a preference for bone marrow derived MHC antigens (Katz et al., 1979, Zinkernagel et al., 1980).
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© 1982 Plenum Press, New York
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Rouse, R.V., Weissman, I.L. (1982). The Principal Cells in the Thymus Expressing MHC Antigens are Epithelial. In: Nieuwenhuis, P., van den Broek, A.A., Hanna, M.G. (eds) In Vivo Immunology. Advances in Experimental Medicine and Biology, vol 149. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-9066-4_55
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DOI: https://doi.org/10.1007/978-1-4684-9066-4_55
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