Abstract
In mice, the development of thymic lymphomas either spontaneously, or after a treatment by irradiation chemicals or retroviruses, raises the question of the interactions between putative oncogenic factors and the normal pathway of T cell differentiation. Lymphomas induced by inoculation of the Radiation Leukemia Virus (RadLV)+ are good experimental models for studying such interactions. The injection of this virus into C57BL/Ka mice results in specific modifications, i.e. overt virus replication and eventual lymphoma development, which are selectively located within the thymus (review: Kaplan, 1977).
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© 1982 Plenum Press, New York
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Boniver, J., Houben-Defresne, MP., Varlet, A., Goffinet, G. (1982). “Thymic Nurse Cells” Contain the First Virus Producing Cells after Inoculation of the Radiation Leukemia Virus in C57BL/Ka Mice. In: Nieuwenhuis, P., van den Broek, A.A., Hanna, M.G. (eds) In Vivo Immunology. Advances in Experimental Medicine and Biology, vol 149. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-9066-4_36
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DOI: https://doi.org/10.1007/978-1-4684-9066-4_36
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