Abstract
The regulatory role of the thymus in the differentiation process of T lymphocytes has been well accepted (1,2). Functional distinct subclasses of T lymphocytes differentiate within the thymic compartment. These cells can be identified by virtue of the expression of Lyt antigens. Thus, T helper and T amplifier cells carry the Lyt-1+, 2-, 3+ phenotype (Lyt-1+ cells), whereas suppressor and cytotoxic T cells carry the Lyt-1-, 2+, 3+ phenotype (Lyt-2,3+ cells). Cantor and Boyse (3) have provided evidence that these cells originate from a precursor cell expressing the Lyt-1+, 2+, 3+ phenotype (Lyt-123+ cells).
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© 1982 Plenum Press, New York
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van Ewijk, W., Jenkinson, E.J., van Soest, P.L., Owen, J.J.T. (1982). Detection of MHC, Thy-1, Lyt-1 And Lyt-2 Antigens in the Developing Mouse Thymus. In: Nieuwenhuis, P., van den Broek, A.A., Hanna, M.G. (eds) In Vivo Immunology. Advances in Experimental Medicine and Biology, vol 149. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-9066-4_33
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DOI: https://doi.org/10.1007/978-1-4684-9066-4_33
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