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Experimental Approaches to Lymphocyte Traffic: Pitfalls of the Tracer Sample Method

  • Chapter
In Vivo Immunology

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 149))

Abstract

The recirculation of lymphocytes between the blood and the tissues can be regarded as occurring in four stages -

  1. 1)

    Selective migration from the blood into particular tissues. This is governed by an unknown number of specific interactions between lymphocytes and vascular endothelium.

  2. 2)

    Segregation of B and T lymphocytes into distinct compartments of peripheral lymphoid tissue.

  3. 3)

    Migration of lymphocytes through interstitial and lymphatic channels to return to the blood.

  4. 4)

    Distribution by the bloodstream to different organs.

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References

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Author information

Authors and Affiliations

  1. Department of Experimental Pathology, University Medical School, Manchester, M13 9PT, UK

    W. L. Ford & M. E. Smith

Authors
  1. W. L. Ford
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  2. M. E. Smith
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Editor information

Editors and Affiliations

  1. University of Groningen, Groningen, The Netherlands

    Paul Nieuwenhuis  & A. A. van den Broek  & 

  2. NCI-Frederick Cancer Research Facility, Frederick, Maryland, USA

    M. G. Hanna Jr.

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© 1982 Plenum Press, New York

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Ford, W.L., Smith, M.E. (1982). Experimental Approaches to Lymphocyte Traffic: Pitfalls of the Tracer Sample Method. In: Nieuwenhuis, P., van den Broek, A.A., Hanna, M.G. (eds) In Vivo Immunology. Advances in Experimental Medicine and Biology, vol 149. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-9066-4_19

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  • DOI: https://doi.org/10.1007/978-1-4684-9066-4_19

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-9068-8

  • Online ISBN: 978-1-4684-9066-4

  • eBook Packages: Springer Book Archive

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