Abstract
Deposit of melanin-like particles in the lymph node of the healthy and diseased human as well as lipomelanic reticulosis of the lymph node associated with the various skin diseases have been reported by many investigators. This experiment was aimed to explain how the melanin reaches the lymph node from the connective tissue. However melanosomes were not put into the skin but into the abdominal cavity of the mice, because the former might injure the lymphatic capillary inducing its changed permeability (1).
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References
Ohkuma, M.: The fine structure and function of the injured lymphatic capillary after injection of saline solution. 3rd International Congress of Lymphology, Belgium, 1970.
Seiji, M., Shimao, K., Birbeck, M.S.C. and Fitzpatrick, T.B.: Subcellular localization of melanin biosyntheais. Annals of N.Y. Academy of Sciences, 100: 497, 1963.
Ohkuma, M.: Fine Structure and function of cutaneous and renal lymphatic capillary. Bullentin Tokyo Med. & Dent. Univ., 17: 103, 1970.
Leak, L.V. and Burke, J.F.: Electron microscopic study of lymphatic capillaries in the removal of connective tissue fluids and particulate substances. Lymphology, 1: 39, 1968.
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© 1977 Plenum Press, New York
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Ohkuma, M. (1977). Lymphatic Transport of Melanosomes from the Tissue to the Lymph Node. An Electron Microscopic Study. In: Mayall, R.C., Witte, M.H. (eds) Progress in Lymphology. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-9030-5_10
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DOI: https://doi.org/10.1007/978-1-4684-9030-5_10
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4684-9032-9
Online ISBN: 978-1-4684-9030-5
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