Sequential Analysis of T Cell-Mediated Cytolysis: A Brief Reminder of Some Possibly Informative Markers at the Recognition and Lethal Hit Stages

  • Pierre Golstein
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 146)


The mechanism of T cell-mediated cytolysis can be considered as a “metabolic” pathway leading to a specialized functional effect, much like the pathways in microorganisms leading to the processing of a given metabolite. The comparison is useful mostly in the sense that it suggests a multi-step process. The latter may be studied genetically.


Effector Cell Conjugate Formation Recognition Stage Glucose Requirement Target Cell Recognition 
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Copyright information

© Plenum Press, New York 1982

Authors and Affiliations

  • Pierre Golstein
    • 1
  1. 1.Centre d’Immunologie INSERM-CNRS de Marseille-LuminyMarseille Cedex 9France

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