Abstract
Alloimmune cytotoxic T cell populations demonstrate exquisite immunologic specificity, killing only target cells which display alloantigens related to those used for immunization (1,2). It was noted some time ago, however, that in the presence of the plant lectins concanavalin A (Con A) and phythohemagglutinin such specificity is not maintained; rather a variety of target cells, including those syngeneic to the effector cell source, are lysed (3–5).
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Green, W.R. (1982). Studies on the Mechanism of Lectin-Dependent T Cell-Mediated Cytolysis: Use of Lens Culinaris Hemagglutinin A to Define the Role of Lectin. In: Clark, W.R., Golstein, P. (eds) Mechanisms of Cell-Mediated Cytotoxicity. Advances in Experimental Medicine and Biology, vol 146. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-8959-0_6
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DOI: https://doi.org/10.1007/978-1-4684-8959-0_6
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