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Efferent Innervation of the Carotid Body and Carotid Sinus in the Guinea Pig

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Chemoreceptors and Chemoreceptor Reflexes

Abstract

Both carotid body chemoreceptors and carotid sinus baroreceptors are influenced by efferent fibres supplied via the sinus nerve and direct sympathetic branches. These efferent fibres were subjected to a histochemical investigation to obtain more information on the possible transmitters and modulators involved in this efferent-afferent interaction.

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References

  • Costa, M., Buffa, R., Furness, J. D., Folsolcia, E. L., 1980, Immunohisto- chemical localization of polypeptides in peripheral autonomic nerves using whole mount preparations. Histochemistry, 65:157.

    Article  Google Scholar 

  • Furness, J. B., and Costa, M., 1975, The use of glyoxylic acid for the fluorescence histochemical localization of catecholamines and S-hydroxy-tryptamine in the whole mount preparations. Histochemistry, 41:335.

    Article  Google Scholar 

  • Gibbins, I. L., Furness, J. B., and Costa, M., 1987, Pathway-specific patterns of the coexistence of substance P, calcitonin gene-related peptide, cholecystokinin and dynorphin in neurons of the dorsal root ganglia of the guinea pig. Cell Tissue Res., 248:417.

    Article  Google Scholar 

  • Kondo, H., Kuramoto, H., and Fujita, T., 1986, Neuropeptide tyrosine-like immunoreactive nerve fibres in the carotid body chemoreceptor of rats. Brain Res., 372:353.

    Article  Google Scholar 

  • Kummer, W., 1987, Calcitonin gene-related peptide-immunoreactive nerve fibres in carotid body and carotid sinus, Exp. Brain Res., 16:84.

    Google Scholar 

  • Kummer, W., 1988, Retrograde neuronal labelling and double-staining immuno- histochemistry of tachykinin- and calcitonin gene-related peptide immunoreactive pathways in the carotid sinus nerve of the guinea pig, J. Auton. Nerv. Syst., 23:131.

    Article  Google Scholar 

  • Kummer, W., and Heym, Ch., 1986, Correlation of neuronal size and peptide immunoreactivity in the guinea-pig trigeminal ganglion. Cell Tissue Res., 245:657.

    Article  Google Scholar 

  • Nielsch, U., and Keen, P., 1989, Reciprocal regulation of tachykinin- and vasoactive intestinal peptide-gene expression in rat sensory neurons following cut and crush injury. Brain Res., 481:25.

    Article  Google Scholar 

  • O’Regan, R. G., 1981, Response of carotid body chemosensory activity and blood flow to stimulation of sympathetic nerves in the cat, J. Physiol. (Lond.), 315:81.

    Google Scholar 

  • O’Regan, R. G., and Acker, H., 1981, Effects of efferent nerves upon total flow, local flow, tissue PO2 and chemoreceptor activity of the cat carotid body, in: “Arterial Chemoreceptors,” C. Balmonte, D. J. Pallot, H. Acker, and S. Fidone, eds., Leicester University Press.

    Google Scholar 

  • Potter, E. K., and McCloskey, D. I., 1987, Excitation of carotid body chemoreceptors by neuropeptide-Y, Resp. Physiol., 67:357.

    Article  Google Scholar 

  • Shehab, S. A. S., and Atkinson, M. E., 1986, Vasoactive intestinal polypeptide increases in the spinal cord after peripheral axotomy of the sciatic nerve originate from primary afferent neurons. Brain Res., 372:37.

    Article  Google Scholar 

  • Torre de la, J. C., 1980, Standardization of the SPG histofluorescence method for tissue monoamines, J. Neurosci. Meth., 3:1.

    Article  Google Scholar 

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© 1990 Plenum Press, New York

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Kummer, W. (1990). Efferent Innervation of the Carotid Body and Carotid Sinus in the Guinea Pig. In: Acker, H., Trzebski, A., O’Regan, R.G. (eds) Chemoreceptors and Chemoreceptor Reflexes. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-8938-5_12

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  • DOI: https://doi.org/10.1007/978-1-4684-8938-5_12

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-8940-8

  • Online ISBN: 978-1-4684-8938-5

  • eBook Packages: Springer Book Archive

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