Abstract
It is a well known fact that humans with a severe kidney impairment, or after removal of both of the organs, develop a life-threatening anemia which can be alleviated by the administration of erythropoietin (EPO). The kidney, however, is apparently not the only source of plasma EPO (Fischer et al., 1962; Waldmann and Rosse, 1962) and Jacobson (1962) estimated that other sites are responsible for as much as 10% of the total overall quantity.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Blessing, M. H., von Kortzfleisch, D., and de Jonge, J. P. A., 1988, Structural changes in the glomus caroticum due to arteriosclerosis, IX. International Symposium on Arterial Chemoreceptors, Park City, Utah, USA.
Bützler, H. O., 1964, Nierenkrankheiten und Erythropoese, Inauguraldissertation, Bonn.
Erslev, A. J., 1960, Erythropoietic function in uremic rabbits, II. Effect of nephrectomy on red cell production and iron metabolism. Acta Haemat., 23:226.
Fisher, J. W., Sanzari, M. P., Birdwell, B. J., and Crook, J. J., 1962, The role of the kidney in erythropoietin production, in: “Erythropoiesis,” L. O. Jacobson, M. Doyle, eds., Grune & Stratton, New York and London.
Gurney, C. W., 1962, Relationship of erythropoietin production to renal abnormalities, “Erythropoiesis,” L. O. Jacobson, M. Doyle, eds., Grune & Stratton, New York and London.
Hagiwara, M., 1987f Ultrastructural immunohistochemical studies on erythropoietin-producing cells in a human renal carcinoma grown in athymic nude mice and primary monolayer cultures, Jap. J. Urology, 78:834.
Jacobson, L. O., 1962, Sites of formation of erythropoietin, “Erythropoiesis,” L. O. Jacobson, M. Doyle, eds., Grune & Stratton, New York and London.
Korst, D. R., Frenkel, E. P., Cousineau, L., and Muirhead, E. E., 1962, Erythropoietin studies in human renal abnormalities. Correlative renal explant attempts in the rat and dog, in: “Erythropoiesis,” L. O. Jacobson, N. Doyle, eds., Grune & Stratton, New York and London.
Latner, A.L., 1938, The carotid sinus and blood regeneration, J. Physiol. (Lond.), 93:75.
Nadji, M., Matsuo, S., Ganjei, P., Ziegels-Weissmann, J., and Penneys, N. S., 1988, Monoclonal antibody ERY-1 identifies in erythroid cells, hepatocellular and renal cell carcincwias. Acta Haemat., 79:68.
Nielsen, O. J., Jespersen, F. F., and Hilden, M., 1988, Erythropoietin-induced secondary polycythemia in a patient with renal cell carcinoma, APMIS, 96:688.
Reissmann, K. R., and Nomura, T., 1962, Erythropoietin formation in isolated kidneys and liver, in: “Erythropoiesis,” L. O. Jacobson, M. Doyle, eds., Grune & Stratton, New York and London.
Schäfer, P. W., 1945, Etiology and treatment of polycythemia vera, Ann. Surg., 122:1098.
Vogt, Ch., Pentz, S., and Rich, I. N., 1989, A role for the macrophage in normal hemopoiesis: III. In vitro and in vivo erythropoietin gene expression in macrophages detected by in situ hybridization, Exp. Hematol., 17:391.
Waldmann, T. A., and Rosse, W. F., 1962, Sites of formation of erythropoietin, in: “Erythropoiesis,” L. O. Jacobson, M. Doyle, eds., Grune & Stratton, New York and London.
Zak, F. G., and Lawson, W., 1982, “The Paraganglionic Chemoreceptor System: Physiology, Pathology, and Clinical Medicine,” Springer Verlag, New York, Heidelberg, Berlin.
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1990 Plenum Press, New York
About this chapter
Cite this chapter
Blessing, M.H., Dumitrescu, E., v. Kortzfleisch, D. (1990). Erythropoietin-Associated Antigen in the Human Carotid Body. In: Acker, H., Trzebski, A., O’Regan, R.G. (eds) Chemoreceptors and Chemoreceptor Reflexes. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-8938-5_11
Download citation
DOI: https://doi.org/10.1007/978-1-4684-8938-5_11
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4684-8940-8
Online ISBN: 978-1-4684-8938-5
eBook Packages: Springer Book Archive