Computerized 3-D Reconstruction of Small Blood Vessels from High Voltage Electron-Micrographs of Thick Serial Cross Sections

  • L. Horn
  • W. S. Krajewski
  • P. K. Paul
  • M. J. Song
  • M. J. Sydor
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 242)


Every cell and organ system in the body depends on the circulation of blood for appropriate nutrients, humoral message exchange, and removal of waste. The heart and the large blood vessels are indispensable as pump and plumbing. Blood flow according to tissue needs, however, and body weight economy in terms of total blood volume, requires complex control mechanisms and an intricate distribution system peripherally, particularly in the microcirculation which consists of vessels less than 100 µ. The smallest arteries and arterioles are generally considered the key vessels mediating the distribution of flow by changing their diameters and thus flow resistance. The structural aspects of these vessels thus become crucial for the understanding of the mechanisms that allow the system to operate in optimal harmony — the harmony that we call good health.


Vascular Smooth Muscle Superior Mesenteric Artery Small Blood Vessel Intravital Microscopy Smooth Muscle Layer 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Plenum Press, New York 1988

Authors and Affiliations

  • L. Horn
    • 1
  • W. S. Krajewski
    • 2
  • P. K. Paul
    • 2
  • M. J. Song
    • 3
  • M. J. Sydor
    • 2
  1. 1.Department of PhysiologyUMDNJ-New Jersey Medical SchoolNewarkUSA
  2. 2.Grad. Div. of Biomed. EngineeringNJITNewarkUSA
  3. 3.Wadsworth Center for Laboratories and ResearchNew York State Department of HealthAlbanyUSA

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