Capillary Ultrastructure and Microcirculatory Function of Malignant Tumors

  • Bernhard Endrich
  • Frithjof Hammersen
  • Konrad Messmer
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 242)


Organisation and recruitment of the vascular system comprises one of the fundamental aspects of tumor biology. In most neoplasms, there is a peculiar arrangement of living cells around some vascular arborizations on which they depend for nutrition, growth and metastasis. For studies of the vascular system in tumors, cellular implants have been employed primarily. Such techniques provided the opportunity to demonstrate distinct morphologic changes induced first in neighboring vessels of the host, with new capillaries sprouting from existing capillaries and venules.1,2,3,4,5


Basal Lamina Capillary Density Tumor Blood Flow Amelanotic Melanoma Vascular Morphology 
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Copyright information

© Plenum Press, New York 1988

Authors and Affiliations

  • Bernhard Endrich
    • 1
    • 2
  • Frithjof Hammersen
    • 1
    • 2
  • Konrad Messmer
    • 1
    • 2
  1. 1.Department of Experimental SurgeryUniversity of HeidelbergGermany
  2. 2.Institute of AnatomyTechnical University of MunichGermany

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