Abstract
The study of vascular permeability has been focused in part on the structure of endothelial cells which line the vascular system. The importance of endothelial cell junctions, fenestra and vesicles in the regulation of vascular permeability is now well established. Newer ultrastructural techniques such as immuno-gold labelling1 and rapid freezing2 have confirmed numerous earlier studies which established that endothelial cell structure regulates the transendothelial transport of solutes.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
A.J. Milici, N.E. Watrous and G.E. Palade, Immunogold Localization of Exogenous Albumin in Murine Myocardial Capillaries, J. Cell. Biol. 103: p. 718 (1986).
R.C. Wagner and S.B. Andrews, Ultrastructure of the Vesicular System in Rapidly Frozen Capillary Endothelium of the Rete Mirabile, J. Ultrastruct. Res. 90:172–182 (1985).
S. Williams, J. Devenny and M. Bitensky, Micropinocytic ingestion of glucosylated albumin by mi-crovessels: Possible role in the pathogenesis of diabetic microangiopathy, Proc. Natl. Acad. Sci. U.S.A. 78:2393–2397 (1981).
R. Wagner and M. Matthews, The isolation and culture of capillary endothelium from epididymalfat, Microvascular Res. 10:286–297 (1975).
S. Williams, D. Greener and N. Solenski, Endocytosis and exocytosis of proteins by capillary endothelium, J. Cell Physiol. 120:157–162 (1984).
R. Wagner, S. Williams, M. Matthews and S. Andrews, Exclusion of albumin from vescicular ingestion by isolated microvessels, Microvascular Res. 19:127–130 (1980).
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1988 Plenum Press, New York
About this chapter
Cite this chapter
Williams, S.K., Rose, D.G. (1988). Carbohydrate Regulated Transendothelial Transport of Proteins. In: Chien, S. (eds) Vascular Endothelium in Health and Disease. Advances in Experimental Medicine and Biology, vol 242. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-8935-4_20
Download citation
DOI: https://doi.org/10.1007/978-1-4684-8935-4_20
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4684-8937-8
Online ISBN: 978-1-4684-8935-4
eBook Packages: Springer Book Archive