Abstract
The motor unit includes the anterior horn cell, nerve fiber, motor end plate and muscle fiber. Varying pathology of any or all parts of the motor unit may produce significant, albeit clinically indistinguishable, trophic changes in the skin, muscle, joints and long bones. In some instances, early changes suggest particular clinical disorders, for example, spinal muscle atrophy and Duchenne’s muscular dystrophy. Quite often the distinguishing features are transitory or not at all present. The onset may occur in infancy, childhood or adulthood and progression may be slow, rapid, stuttering or quickly arrested, and these factors modify the extent of pathology and subsequent trophic changes. Muscles may become flaccid, firm or knotty on palpation.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
APPENZELLER, O., and G. OGIN. Pathogenesis of muscular dystrophies: Sympathetic neurovascular components. Arch. Neurol. 32:2–4, 1975.
BRIMIJOIN, S., P. CAPEK, and P. J. DYCK. Axonal transport of dopamine β-hydroxylase by human sural nerves in vitro. Science 180:1295–1297, 1973.
COËRS, C., and N. TELLERMAN-TAPPET. Morphological changes of motor units in Duchenne’s muscular dystrophy. Arch. Neurol. 34: 396–402, 1977.
DÉJÉRINE, J., and J. SOTTAS. Sur la nevrité: Interstitielle, hypertrophique et progressive de l’enfance. C. R. Soc. Biol., Paris 45:63–70, 1893.
DUBOWITZ, V., and M. H. BROOKE. Muscle Biopsy: A Modem Approach. London: W. B. Saunders, 1973, p. 154–158.
DYCK, P. J., P. K. THOMAS, and E. H. LAMBERT. Peripheral Neuropathy, vol. 2. Philadelphia: W. B. Saunders Co., 1975, p. 794–804.
EULENBURG, A. Diseases of the nervous system. In: Cyclopedia of the Practice of Medicine, vol. 14, edited by R. A. Ziemssen. (Publisher unknown) 1877, p. 153–179.
HAUSMANOWA-PETRUSEWICZ, I., W. ASKANAS, B. BADURSKA, B. EMERYK, A. FIDZIANSKA, W. GARBALINSKA, L. HETNARSKA, H. JEDRZEJOWSKA, Z. KAMIENIECKA, I. NIEBROJ-DOBOSZ, J. PROT, and E. SAWICKA. Infantile and juvenile spinal muscular atrophy. J. Neurol. Sci. 6:269–287, 1968.
KUGELBURG, E., and L. WELANDER. Hereditofamilial juvenile muscular atrophy simulating muscular dystrophy. Arch. Neurol. Psychiat. 75:500–505, 1956.
MAWATARI, S., M. SCHONBERG, and M. OLARTE. Biochemical abnormalities of erythrocyte membranes in Duchenne’s dystrophy. Arch. Neurol. 33:489–494, 1976.
MCCOMAS, A. J., R.E.P. SICA, and A.R.M. UPTON. Multiple muscle analysis of motor units in muscular dystrophy. Arch. Neurol. 30:249–251, 1974.
OHTA, M., R. D. ELLEFSON, E. H. LAMBERT, and P. J. DYCK. Hereditary sensory neuropathy, Type III. Arch. Neurol. 29:23–37, 1973.
PIERSON, C. M., and S. CURRIE. Disorders of Voluntary Muscle, edited by John Walton. London: Churchill Livingston, 1974, p. 627–634.
ROWLAND, L. P. Pathogenesis of muscular dystrophies. Arch. Neurol. 33:315–321, 1976.
SARNAT, H. B., and S. W. SELBERT. Maturational arrest of fetal muscle in neonatal myotonic dystrophy. Arch. Neurol. 33: 466–474, 1976.
STANBURY, J. B., J. B. WYNGAARDEN, and D. S. FREDRICKSON. The Metabolic Basis of Inherited Disease, 3rd ed. New York: McGraw-Hill, 1972.
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1978 Plenum Press, New York
About this chapter
Cite this chapter
Nigro, M.A. (1978). Trophic Changes in Afflictions of the Motor Unit. In: Korr, I.M. (eds) The Neurobiologic Mechanisms in Manipulative Therapy. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-8902-6_19
Download citation
DOI: https://doi.org/10.1007/978-1-4684-8902-6_19
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4684-8904-0
Online ISBN: 978-1-4684-8902-6
eBook Packages: Springer Book Archive