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Peptides in Parkinson’s Disease

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Parkinson’s Disease—II

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 113))

Summary

Peptides have found a progressively more important role in the biochemistry and physiology of the brain in recent years. Many possess neurological and behavioral actions in addition to their function in endocrinology. This paper reviews the formation and distribution, as well as the neurological action, of peptides probably involved in Parkinson’s disease: β-LPH and its derivatives (MSH, ACTH4+10, β-endorphin). It also recounts the experience of many authors with prolyl-leucyl-glycine-amide (PLG) in that disease. Finally we propose a new theory of the etiology of Parkinson’s disease, based on a postulated deficiency in the important trophic function upon catecholaminergic neurons of A.P.U.D. cells.

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Author information

Authors and Affiliations

  1. Department of Neurobiology, Clinical Research Institute of Montreal, Montreal, Quebec, Canada, H2W 1R7

    André Barbeau

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  1. André Barbeau
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Editor information

Editors and Affiliations

  1. University of Southern California, Los Angeles, California, USA

    Caleb E. Finch

  2. Texas Tech University School of Medicine, Lubbock, Texas, USA

    David E. Potter  & Alexander D. Kenny  & 

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© 1978 Plenum Press, New York

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Barbeau, A. (1978). Peptides in Parkinson’s Disease. In: Finch, C.E., Potter, D.E., Kenny, A.D. (eds) Parkinson’s Disease—II. Advances in Experimental Medicine and Biology, vol 113. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-8893-7_6

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  • DOI: https://doi.org/10.1007/978-1-4684-8893-7_6

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-8895-1

  • Online ISBN: 978-1-4684-8893-7

  • eBook Packages: Springer Book Archive

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