Abstract
Hypochondroplasia (H.) has been considered for a long time a mild form of achondroplasia (A.). Both entities, on the contrary, are definitely two separate conditions, hypochondroplastic parents having never had children with A. and vice versa. H. however may exhibit clinical and radiographic variations, so that in a severe form, it may resemble A. H. is not a rare hereditary chondrodystrophy, although relatively few cases have been reported in the literature. This probably depends on the numerous though mild clinical and radiological features, which suffer from a lack of specificity and are also seen in other types of disproportionate dwarfism.
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References
G. Gemme, G. Pinelli, E. Bonioli, P. Sbolgi and M. A. Bonzano, Aspetti clinici e radiologici dell’ipocondroplasia. Min. Ped. 32:237 (1980).
B. D. Hall and J. Spranger, Hypochondroplasia: clinical and radiological aspects in 39 cases. Radiology 133:95 (1979).
V. C. Hinck, C. E. Hopkins and W. M. Clark, Sagittal diameter of the lumbar spinal canal in children and adults. Radiology 85: 929 (1965).
V. C. Hinck, W. M. Clark, Jr and C. E. Hopkins, Normal interpeduncolate distances (minimum and maximum) in children and adults, AJR 97:141 (1966).
K. Kozlowski, Hypochondroplasia, Prog. Pediatr. Radiol. 4:238 (1973).
F. Oberklaid, D. M. Banks, F. Jensen, L. Stace and S. Rossahandler, Achondroplasia and hypochondroplasia. Journal of Medical Genetics 16:140 (1979).
M. M. Maresh, Linear growth of the long bones of the extremities from infancy through adolescence. Am. J. Pis. Child. 89:725 (1955).
V. A. McKusick, T. E. Kelly and J. P. Dorst, Observations suggesting allelism of the achondroplasia apd hypochondroplasia genes. Journal of Medical Genetics 10:11 (1973).
A. K. Poznanski, The hand in radiologic diagnosis, Philadelphia, Saunders, vol. 1 (1984).
F. N. Silverman, A differential diagnosis of achondroplasia, Radiol. Clin. N. Amer. 6:223 (1968).
F. N. Silverman, Personal Communication.
B. A. Walker, J. L. Murdoch, V. A. McKusick, L. O. Langer, R. K. Beals, Hypochondroplasia, Am. J. Pis. Child. 122:95 (1971).
R. Wynne-Pavies, W. K. Walsh and J. Gormley, Achondroplasia and hypo chondroplasia. Clinical variation and spinal stenosis, J. Bone Joint Surg. (BR) 63–B:508 (1981).
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© 1988 Plenum Press, New York
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Fasanelli, S. (1988). Hypochondroplasia: Radiological Diagnosis and Differential Diagnosis. In: Nicoletti, B., Kopits, S.E., Ascani, E., McKusick, V.A., Dryburgh, S.C. (eds) Human Achondroplasia. Basic Life Sciences, vol 48. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-8712-1_22
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DOI: https://doi.org/10.1007/978-1-4684-8712-1_22
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